SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ib8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1ib8 CONSERVED PROTEIN
SP14.3
(Streptococcus
pneumoniae) 		5 / 9 PHE A  76
TYR A  80
ILE A  31
VAL A  14
ILE A  10
 None
 1.36A 1gebA-1ib8A:
0.0		 1gebA-1ib8A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1ib8 CONSERVED PROTEIN
SP14.3
(Streptococcus
pneumoniae) 		3 / 3 ASP A 139
VAL A 146
PRO A 149
 None
 0.78A 2avvA-1ib8A:
undetectable		 2avvA-1ib8A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1ib8 CONSERVED PROTEIN
SP14.3
(Streptococcus
pneumoniae) 		5 / 12 LEU A  93
LEU A 133
MET A 135
VAL A 153
ALA A 156
 None
 1.25A 4x1iB-1ib8A:
undetectable		 4x1iB-1ib8A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 1ib8 CONSERVED PROTEIN
SP14.3
(Streptococcus
pneumoniae) 		4 / 6 PHE A 121
LYS A 119
GLY A 110
ALA A 156
 None
 1.12A 4yshB-1ib8A:
undetectable		 4yshB-1ib8A:
18.96