SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ibj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 THR A 155
SER A 311
SER A 156
LEU A 187
VAL A 191
 None
None
PLP  A1400 (-3.6A)
None
None
 1.33A 1q23D-1ibjA:
1.4
1q23E-1ibjA:
1.4		 1q23D-1ibjA:
18.45
1q23E-1ibjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 10 THR A 155
SER A 311
SER A 156
LEU A 187
VAL A 191
 None
None
PLP  A1400 (-3.6A)
None
None
 1.32A 1q23E-1ibjA:
1.1		 1q23E-1ibjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 11 THR A 155
SER A 311
SER A 156
LEU A 187
VAL A 191
 None
None
PLP  A1400 (-3.6A)
None
None
 1.36A 1q23F-1ibjA:
1.6		 1q23F-1ibjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 11 THR A 155
SER A 311
SER A 156
LEU A 187
VAL A 191
 None
None
PLP  A1400 (-3.6A)
None
None
 1.36A 1q23G-1ibjA:
1.8		 1q23G-1ibjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 10 THR A 155
SER A 311
SER A 156
LEU A 187
VAL A 191
 None
None
PLP  A1400 (-3.6A)
None
None
 1.38A 1q23K-1ibjA:
1.6		 1q23K-1ibjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 10 THR A 134
ASP A 136
GLU A 139
GLY A 131
LEU A 313
 None
 1.00A 1x7pA-1ibjA:
undetectable
1x7pB-1ibjA:
undetectable		 1x7pA-1ibjA:
21.63
1x7pB-1ibjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 6 ASN A 254
LEU A 291
LEU A 142
ILE A 271
 None
 0.95A 1z95A-1ibjA:
undetectable		 1z95A-1ibjA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 7 LEU A 455
PHE A 400
ILE A 342
GLU A 446
 None
 0.89A 2opxA-1ibjA:
2.1		 2opxA-1ibjA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 8 LEU A 207
VAL A 221
LEU A 223
VAL A 175
 None
 0.87A 2zujA-1ibjA:
undetectable		 2zujA-1ibjA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 10 ILE A 239
TRP A 222
THR A 204
VAL A 210
ILE A 214
 None
 1.41A 3kpbD-1ibjA:
undetectable		 3kpbD-1ibjA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 9 LEU A 313
VAL A 286
LEU A 142
ILE A 280
ALA A 281
 None
 1.05A 3mdvA-1ibjA:
undetectable		 3mdvA-1ibjA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 108
TYR A 109
TYR A 125
ALA A 137
LEU A 322
 None
 1.11A 3ou6D-1ibjA:
1.9		 3ou6D-1ibjA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 108
TYR A 109
TYR A 125
ALA A 137
LEU A 322
 None
 1.12A 3ou7A-1ibjA:
undetectable		 3ou7A-1ibjA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 108
TYR A 109
TYR A 125
ALA A 137
LEU A 322
 None
 1.15A 3ou7C-1ibjA:
undetectable		 3ou7C-1ibjA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 108
TYR A 109
TYR A 125
ALA A 137
LEU A 322
 None
 1.11A 3ou7D-1ibjA:
undetectable		 3ou7D-1ibjA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 ILE A 280
SER A 184
ALA A 160
LEU A 251
VAL A 164
 None
PLP  A1400 ( 4.5A)
None
None
None
 0.98A 3w67C-1ibjA:
0.0		 3w67C-1ibjA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 6 THR A 205
ASN A 203
GLY A 177
ASP A 179
 None
 1.09A 3w9tE-1ibjA:
undetectable		 3w9tE-1ibjA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 8 GLY A 444
ASN A 338
PHE A 400
ILE A 441
 None
 0.99A 4j4vC-1ibjA:
0.0		 4j4vC-1ibjA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 7 ASN A 254
LEU A 291
LEU A 142
ILE A 271
 None
 1.04A 4okwA-1ibjA:
0.0		 4okwA-1ibjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 459
TYR A 345
LEU A 346
THR A 384
 None
 1.06A 4paeA-1ibjA:
0.0		 4paeA-1ibjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 HIS A 363
GLY A 359
HIS A 369
PHE A 370
MET A 257
 None
 1.34A 4qa0A-1ibjA:
2.4		 4qa0A-1ibjA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 12 HIS A 274
ALA A 159
ALA A 160
VAL A 164
GLY A 312
 None
 0.82A 5igtA-1ibjA:
0.0		 5igtA-1ibjA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 4 SER A 162
ALA A 159
GLN A 306
THR A 155
 None
 1.17A 5n0rA-1ibjA:
0.0		 5n0rA-1ibjA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 4 SER A 162
ALA A 159
GLN A 306
THR A 155
 None
 1.19A 5n0sA-1ibjA:
0.0		 5n0sA-1ibjA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 4 SER A 162
ALA A 159
GLN A 306
THR A 155
 None
 1.16A 5n0wA-1ibjA:
0.0		 5n0wA-1ibjA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 5 SER A 162
ALA A 159
GLN A 306
THR A 155
 None
 1.15A 5n0wB-1ibjA:
0.0		 5n0wB-1ibjA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 4 SER A 162
ALA A 159
GLN A 306
THR A 155
 None
 1.17A 5n0xA-1ibjA:
1.9		 5n0xA-1ibjA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		4 / 5 SER A 162
ALA A 159
GLN A 306
THR A 155
 None
 1.13A 5n4iA-1ibjA:
undetectable		 5n4iA-1ibjA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 7 VAL A 409
ILE A 332
MET A 273
ARG A 323
ALA A 276
 None
None
PLP  A1400 ( 4.7A)
None
None
 1.40A 6hd6B-1ibjA:
undetectable		 6hd6B-1ibjA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1ibj CYSTATHIONINE
BETA-LYASE
(Arabidopsis
thaliana) 		5 / 10 MET A 257
GLY A 268
SER A 240
ASN A 254
VAL A 252
 None
 1.22A 6hu9L-1ibjA:
0.0
6hu9P-1ibjA:
0.0
6hu9T-1ibjA:
0.0		 6hu9L-1ibjA:
25.20
6hu9P-1ibjA:
21.30
6hu9T-1ibjA:
9.53