SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ibv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1ibv HISTIDINE
DECARBOXYLASE ALPHA
CHAIN
(Lactobacillus
sp.
30A) 		3 / 3 ARG B  89
GLU B 286
SER B 238
 None
 0.90A 2xctD-1ibvB:
undetectable		 2xctD-1ibvB:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1ibv HISTIDINE
DECARBOXYLASE ALPHA
CHAIN
(Lactobacillus
sp.
30A) 		4 / 8 ARG B 218
SER B 193
VAL B 101
TYR B  93
 None
 1.34A 2y05A-1ibvB:
undetectable
2y05B-1ibvB:
undetectable		 2y05A-1ibvB:
20.82
2y05B-1ibvB:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1ibv HISTIDINE
DECARBOXYLASE ALPHA
CHAIN
(Lactobacillus
sp.
30A) 		3 / 3 ASP B 279
THR B 289
GLU B 286
 None
 0.66A 2zifB-1ibvB:
undetectable		 2zifB-1ibvB:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 1ibv HISTIDINE
DECARBOXYLASE ALPHA
CHAIN
(Lactobacillus
sp.
30A) 		4 / 8 PHE B 195
VAL B  90
ILE B  91
ILE B 150
 None
 0.98A 5hw8H-1ibvB:
undetectable		 5hw8H-1ibvB:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 1ibv HISTIDINE
DECARBOXYLASE ALPHA
CHAIN
(Lactobacillus
sp.
30A) 		4 / 6 ALA B 104
SER B  98
GLY B  92
ILE B 182
 None
 0.87A 6f8cA-1ibvB:
undetectable		 6f8cA-1ibvB:
20.59