SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ibx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 1ibx DNA FRAGMENTATION
FACTOR 40
CHIMERA OF IGG
BINDING PROTEIN G
AND DNA
FRAGMENTATION FACTOR
45
(Homo
sapiens;
Streptococcus
sp.;
Homo
sapiens) 		5 / 10 GLY A  20
PHE A  19
LEU B  39
THR B  60
LEU B  61
 None
 1.47A 1a8uB-1ibxA:
undetectable		 1a8uB-1ibxA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 1ibx CHIMERA OF IGG
BINDING PROTEIN G
AND DNA
FRAGMENTATION FACTOR
45
(Homo
sapiens;
Streptococcus
sp.) 		4 / 8 ALA B  89
VAL B  59
LEU B  50
HIS B  32
 None
 0.79A 2it4A-1ibxB:
undetectable		 2it4A-1ibxB:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1ibx CHIMERA OF IGG
BINDING PROTEIN G
AND DNA
FRAGMENTATION FACTOR
45
(Homo
sapiens;
Streptococcus
sp.) 		3 / 3 SER B  37
ALA B  35
VAL B  34
 None
 0.53A 4o2bA-1ibxB:
undetectable		 4o2bA-1ibxB:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1ibx CHIMERA OF IGG
BINDING PROTEIN G
AND DNA
FRAGMENTATION FACTOR
45
(Homo
sapiens;
Streptococcus
sp.) 		3 / 3 SER B  37
ALA B  35
VAL B  34
 None
 0.64A 4o2bC-1ibxB:
undetectable		 4o2bC-1ibxB:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1ibx DNA FRAGMENTATION
FACTOR 40
CHIMERA OF IGG
BINDING PROTEIN G
AND DNA
FRAGMENTATION FACTOR
45
(Homo
sapiens;
Streptococcus
sp.;
Homo
sapiens) 		3 / 3 ARG A  31
LYS A  32
ARG B  43
 None
 1.27A 6c06D-1ibxA:
undetectable		 6c06D-1ibxA:
undetectable