SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1id1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		5 / 11 SER A  14
ASN A  19
LEU A  16
ALA A 106
LEU A 125
 None
 1.41A 1hwkB-1id1A:
0.0		 1hwkB-1id1A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		5 / 11 SER A  14
ASN A  19
LEU A  16
ALA A 106
LEU A 125
 None
 1.41A 1hwkA-1id1A:
undetectable		 1hwkA-1id1A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		5 / 11 SER A  14
ASN A  19
LEU A  16
ALA A 106
LEU A 125
 None
 1.40A 1hwkD-1id1A:
0.0		 1hwkD-1id1A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		5 / 11 SER A  14
ASN A  19
LEU A  16
ALA A 106
LEU A 125
 None
 1.40A 1hwkC-1id1A:
0.0		 1hwkC-1id1A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		5 / 12 ASP A 100
ASP A 122
ILE A  77
ILE A  71
THR A 103
 None
 1.46A 1kijA-1id1A:
undetectable		 1kijA-1id1A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		4 / 8 ASP A  84
ASN A  87
SER A 126
ALA A  79
 None
 1.03A 1rqpC-1id1A:
undetectable		 1rqpC-1id1A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		4 / 8 ASP A  84
ASN A  87
SER A 126
ALA A  79
 None
 1.02A 1rqpA-1id1A:
undetectable		 1rqpA-1id1A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		4 / 8 ASP A  84
ASN A  87
SER A 126
ALA A  79
 None
 1.03A 2v7uA-1id1A:
undetectable		 2v7uA-1id1A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		4 / 6 ARG A  73
ILE A  71
ILE A 123
LEU A  80
 None
 0.91A 2xkwB-1id1A:
0.0		 2xkwB-1id1A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1id1 PUTATIVE POTASSIUM
CHANNEL PROTEIN
(Escherichia
coli) 		4 / 8 ASP A  84
ASN A  87
ALA A  88
VAL A  91
 None
 0.32A 4zbqA-1id1A:
0.5		 4zbqA-1id1A:
14.73