SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1id2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 VAL A  24
VAL A  22
TRP A  46
 None
 0.72A 1av2A-1id2A:
undetectable
1av2B-1id2A:
undetectable		 1av2A-1id2A:
8.89
1av2B-1id2A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.26A 1oe1A-1id2A:
3.6		 1oe1A-1id2A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		5 / 5 HIS A  54
CYH A  93
PRO A  95
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
None
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.75A 1oe2A-1id2A:
5.9		 1oe2A-1id2A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.28A 1oe3A-1id2A:
3.7		 1oe3A-1id2A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		5 / 11 VAL A 105
VAL A 103
TYR A  91
GLU A  85
ILE A  81
 None
 1.38A 1t6zB-1id2A:
undetectable		 1t6zB-1id2A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 VAL A  24
VAL A  22
TRP A  46
 None
 0.78A 1w5uA-1id2A:
undetectable
1w5uB-1id2A:
undetectable		 1w5uA-1id2A:
8.89
1w5uB-1id2A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.57A 2fqdA-1id2A:
2.8		 2fqdA-1id2A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.55A 2fqeA-1id2A:
2.8		 2fqeA-1id2A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.58A 2fqfA-1id2A:
2.8		 2fqfA-1id2A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.58A 2fqgA-1id2A:
2.7		 2fqgA-1id2A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 VAL A  22
TRP A  46
VAL A  24
 None
 0.83A 2izqC-1id2A:
undetectable
2izqD-1id2A:
undetectable		 2izqC-1id2A:
8.89
2izqD-1id2A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.29A 2xxgA-1id2A:
5.7		 2xxgA-1id2A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		5 / 5 HIS A  54
CYH A  93
PRO A  95
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
None
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.80A 2xxgC-1id2A:
5.9		 2xxgC-1id2A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 5 ILE A  26
PHE A  83
PHE A  58
TYR A  91
 None
 1.39A 3em0A-1id2A:
0.0		 3em0A-1id2A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 1id2 AMICYANIN
(Paracoccus
versutus) 		5 / 12 VAL A 105
VAL A  36
ILE A  81
VAL A  44
VAL A  22
 None
 1.26A 3iw1A-1id2A:
undetectable		 3iw1A-1id2A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 GLY A 101
TRP A  46
VAL A  24
 None
 0.70A 3n62B-1id2A:
undetectable		 3n62B-1id2A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 GLY A 101
TRP A  46
VAL A  24
 None
 0.72A 3n65B-1id2A:
undetectable		 3n65B-1id2A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 GLY A 101
TRP A  46
VAL A  24
 None
 0.71A 3n66B-1id2A:
undetectable		 3n66B-1id2A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 7 PHE A  83
THR A  43
ASN A  84
ILE A   4
 None
 1.05A 3t01A-1id2A:
undetectable		 3t01A-1id2A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 1id2 AMICYANIN
(Paracoccus
versutus) 		4 / 4 HIS A  54
CYH A  93
HIS A  96
MET A  99
 CU  A 107 (-3.1A)
CU  A 107 (-2.0A)
CU  A 107 (-3.3A)
CU  A 107 (-2.8A)
 0.57A 4ef3A-1id2A:
2.9		 4ef3A-1id2A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 GLY A 101
TRP A  46
VAL A  24
 None
 0.68A 5vuoB-1id2A:
undetectable		 5vuoB-1id2A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1id2 AMICYANIN
(Paracoccus
versutus) 		3 / 3 TYR A  31
HIS A  54
MET A  73
 None
CU  A 107 (-3.1A)
None
 1.10A 6af6A-1id2A:
undetectable		 6af6A-1id2A:
15.49