SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1id5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1id5 THROMBIN
(Bos
taurus) 		6 / 8 HIS H  57
ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.66A 1aq7A-1id5H:
33.6		 1aq7A-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		7 / 9 ASP H 189
ALA H 190
GLU H 192
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.41A 1bcuH-1id5H:
43.3		 1bcuH-1id5H:
87.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		7 / 9 ASP H 189
ALA H 190
SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.45A 1bcuH-1id5H:
43.3		 1bcuH-1id5H:
87.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))		 1id5 THROMBIN
(Bos
taurus) 		6 / 9 HIS H  57
ILE H 174
ASP H 189
GLU H 192
TRP H 215
GLY H 226
 None
 0.64A 1dwcH-1id5H:
43.0		 1dwcH-1id5H:
87.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DWC_H_MITH1_1
(ALPHA-THROMBIN
(LARGE SUBUNIT))		 1id5 THROMBIN
(Bos
taurus) 		6 / 9 HIS H  57
ILE H 174
ASP H 189
SER H 195
TRP H 215
GLY H 226
 None
 0.59A 1dwcH-1id5H:
43.0		 1dwcH-1id5H:
87.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		7 / 12 HIS H  57
ASP H 189
SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.69A 1etrH-1id5H:
43.2		 1etrH-1id5H:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		6 / 12 LEU H  99
ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.94A 1etrH-1id5H:
43.2		 1etrH-1id5H:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1id5 THROMBIN
(Bos
taurus) 		5 / 8 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.48A 1f5lA-1id5H:
34.9		 1f5lA-1id5H:
31.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1id5 THROMBIN
(Bos
taurus) 		5 / 10 SER H 195
SER H 214
ILE H 212
GLY H 211
GLY H 226
 None
 1.27A 1mehA-1id5H:
undetectable		 1mehA-1id5H:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1id5 THROMBIN
(Bos
taurus) 		3 / 3 PHE H 199
LEU H 162
LEU H 130
 None
TRS  H 800 ( 4.9A)
TRS  H 800 ( 4.4A)
 0.62A 1mx1E-1id5H:
undetectable		 1mx1E-1id5H:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1id5 THROMBIN
(Bos
taurus) 		4 / 6 GLY H 142
GLN H 156
VAL H 138
ALA H 190
 None
 0.85A 1p6kA-1id5H:
undetectable		 1p6kA-1id5H:
21.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TNL_A_TPAA900_1
(TRYPSIN)		 1id5 THROMBIN
(Bos
taurus) 		5 / 6 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.47A 1tnlA-1id5H:
34.3		 1tnlA-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H9T_H_SVRH301_1
(THROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		5 / 11 HIS H  91
ARG H  93
ARG H 101
TRP H 237
VAL H 241
 None
 1.12A 2h9tH-1id5H:
41.6		 2h9tH-1id5H:
87.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 1id5 THROMBIN
(Bos
taurus) 		5 / 6 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.41A 2otvA-1id5H:
34.4		 2otvA-1id5H:
37.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1id5 THROMBIN
(Bos
taurus) 		6 / 12 GLY H 142
GLY H 196
GLY H 193
THR H  54
LEU H  53
VAL H  31
 None
 1.35A 2oxtD-1id5H:
undetectable		 2oxtD-1id5H:
20.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1id5 THROMBIN
(Bos
taurus) 		8 / 12 ASP H 189
ALA H 190
SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
TYR H 228
 None
 0.41A 2p16A-1id5H:
35.3		 2p16A-1id5H:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1id5 THROMBIN
(Bos
taurus) 		5 / 8 ASP H 189
SER H 195
VAL H 213
GLY H 216
GLY H 226
 None
 0.49A 2vinA-1id5H:
35.1		 2vinA-1id5H:
31.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 1id5 THROMBIN
(Bos
taurus) 		9 / 12 ASP H 189
ALA H 190
SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 219
GLY H 226
TYR H 228
 None
 0.44A 2w26A-1id5H:
35.1		 2w26A-1id5H:
40.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BF6_H_SVRH301_1
(THROMBIN, HEAVY
CHAIN)		 1id5 THROMBIN
(Bos
taurus) 		6 / 11 HIS H  91
PRO H  92
ARG H  93
ARG H 101
TRP H 237
VAL H 241
 None
 0.93A 3bf6H-1id5H:
42.5		 3bf6H-1id5H:
87.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1id5 THROMBIN
(Bos
taurus) 		6 / 11 HIS H  57
ASP H 189
SER H 195
TRP H 215
GLY H 216
GLY H 226
 None
 0.53A 3gy3A-1id5H:
32.7		 3gy3A-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 1id5 THROMBIN
(Bos
taurus) 		6 / 11 LEU H  99
ASP H 189
SER H 195
TRP H 215
GLY H 216
GLY H 226
 None
 0.94A 3gy3A-1id5H:
32.7		 3gy3A-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1id5 THROMBIN
(Bos
taurus) 		5 / 6 SER H 195
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.47A 3rxfA-1id5H:
13.3		 3rxfA-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 1id5 THROMBIN
(Bos
taurus) 		4 / 5 ASP H 189
SER H 195
VAL H 213
GLY H 226
 None
 0.56A 3rxhA-1id5H:
34.1		 3rxhA-1id5H:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_D_15UD402_1
(PROTHROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		7 / 12 HIS H  57
ILE H 174
ASP H 189
ALA H 190
VAL H 213
TRP H 215
GLY H 226
 None
 0.40A 4hfpD-1id5H:
42.4		 4hfpD-1id5H:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HFP_D_15UD402_1
(PROTHROMBIN)		 1id5 THROMBIN
(Bos
taurus) 		5 / 12 LEU H  99
ASP H 189
ALA H 190
VAL H 213
GLY H 226
 None
 0.66A 4hfpD-1id5H:
42.4		 4hfpD-1id5H:
87.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1id5 THROMBIN
(Bos
taurus) 		4 / 8 LEU H 162
GLY H 133
GLU H 164
GLU H 186
 TRS  H 800 ( 4.9A)
None
None
None
 0.80A 4rjdA-1id5H:
undetectable
4rjdB-1id5H:
undetectable		 4rjdA-1id5H:
13.73
4rjdB-1id5H:
13.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 1id5 THROMBIN
(Bos
taurus) 		6 / 12 HIS H  57
ALA H 190
VAL H 213
TRP H 215
GLY H 216
GLY H 226
 None
 0.73A 4rn6B-1id5H:
35.7		 4rn6B-1id5H:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 1id5 THROMBIN
(Bos
taurus) 		5 / 12 LEU H  99
ALA H 190
VAL H 213
GLY H 216
GLY H 226
 None
 0.88A 4rn6B-1id5H:
35.7		 4rn6B-1id5H:
87.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1id5 THROMBIN
(Bos
taurus) 		5 / 12 GLY H 188
ALA H 190
PHE H 181
TYR H 228
VAL H 213
 None
 1.23A 5hw4C-1id5H:
undetectable		 5hw4C-1id5H:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1id5 THROMBIN
(Bos
taurus) 		5 / 9 LEU H  53
ILE H 212
GLY H 196
GLY H  43
LEU H 105
 None
 0.99A 5o96A-1id5H:
undetectable
5o96B-1id5H:
undetectable		 5o96A-1id5H:
21.03
5o96B-1id5H:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1id5 THROMBIN
(Bos
taurus) 		4 / 7 VAL H 200
VAL H 231
PRO H 124
TYR H 208
 None
 0.97A 5x80C-1id5H:
0.0
5x80D-1id5H:
0.0		 5x80C-1id5H:
18.77
5x80D-1id5H:
18.77