SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ieh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1ieh BRUC.D4.4
(Lama
glama) 		4 / 6 LEU A 104
TRP A 107
LEU A   4
PHE A  27
 None
 1.30A 1rukH-1iehA:
14.6
1rukL-1iehA:
12.2		 1rukH-1iehA:
30.09
1rukL-1iehA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.43A 1usqA-1iehA:
1.4		 1usqA-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.43A 1usqF-1iehA:
undetectable		 1usqF-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.42A 2jkjE-1iehA:
undetectable		 2jkjE-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.41A 2jklA-1iehA:
1.6		 2jklA-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.41A 2jklC-1iehA:
1.5		 2jklC-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.40A 2jklD-1iehA:
1.6		 2jklD-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.40A 2jklE-1iehA:
undetectable		 2jklE-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1ieh BRUC.D4.4
(Lama
glama) 		5 / 7 GLY A  54
PRO A  53
THR A  58
ILE A  51
GLY A  56
 None
 1.41A 2jklF-1iehA:
0.0		 2jklF-1iehA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1ieh BRUC.D4.4
(Lama
glama) 		4 / 8 SER A  25
ASN A  77
GLY A 108
GLN A   5
 None
 1.02A 4af0A-1iehA:
undetectable		 4af0A-1iehA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 1ieh BRUC.D4.4
(Lama
glama) 		4 / 8 LEU A  18
ALA A   6
VAL A  12
TYR A  94
 None
 1.03A 5nu7A-1iehA:
undetectable		 5nu7A-1iehA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 1ieh BRUC.D4.4
(Lama
glama) 		3 / 3 VAL A  64
TYR A  60
GLU A  46
 None
 0.96A 5zmqD-1iehA:
0.0
5zmqE-1iehA:
undetectable		 5zmqD-1iehA:
22.29
5zmqE-1iehA:
17.16