SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ifg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 1ifg ECOTIN
(Escherichia
coli) 		4 / 8 SER A  79
VAL A  81
SER A  82
ASN A  51
 None
 1.22A 1hwkC-1ifgA:
undetectable		 1hwkC-1ifgA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 1ifg ECOTIN
(Escherichia
coli) 		4 / 8 SER A  79
VAL A  81
SER A  82
ASN A  51
 None
 1.21A 1hwkD-1ifgA:
undetectable		 1hwkD-1ifgA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 1ifg ECOTIN
(Escherichia
coli) 		4 / 4 LEU A 101
GLY A 105
LEU A  40
GLU A  39
 None
 1.01A 3tgvB-1ifgA:
0.0		 3tgvB-1ifgA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1ifg ECOTIN
(Escherichia
coli) 		5 / 8 GLY A  57
GLY A  56
GLY A  43
LEU A  46
VAL A 123
 None
 1.11A 3v1nA-1ifgA:
undetectable		 3v1nA-1ifgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1ifg ECOTIN
(Escherichia
coli) 		3 / 3 TYR A 127
GLN A  30
TRP A 130
 None
 1.09A 4kn2C-1ifgA:
undetectable		 4kn2C-1ifgA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1ifg ECOTIN
(Escherichia
coli) 		4 / 7 MET A 106
GLU A  39
TYR A 109
GLU A 133
 None
 1.09A 4mj8C-1ifgA:
undetectable		 4mj8C-1ifgA:
20.48