SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1igj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 1igj IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 5 HIS B  41
SER B  87
SER B  84
VAL B 111
 None
 1.45A 4a99D-1igjB:
undetectable		 4a99D-1igjB:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1igj IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 SER B 216
ALA B 211
VAL B 210
 None
 0.69A 4o2bC-1igjB:
undetectable		 4o2bC-1igjB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1igj IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 SER B 216
ALA B 211
VAL B 210
 None
 0.57A 5eypA-1igjB:
undetectable		 5eypA-1igjB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1igj IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 8 VAL B 121
ALA B 118
THR B 217
VAL B 152
VAL B 210
 None
 1.40A 5l94A-1igjB:
undetectable		 5l94A-1igjB:
18.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 1igj IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 TYR B  59
GLY B  65
THR B  68
 None
 0.16A 6cjkB-1igjB:
15.7		 6cjkB-1igjB:
54.30