SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1igo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 7 THR A 178
LEU A 180
GLY A  51
LEU A 205
 None
 1.07A 1gtiD-1igoA:
undetectable		 1gtiD-1igoA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 7 VAL A 116
THR A 115
PHE A 114
THR A 113
 None
 1.22A 2kotA-1igoA:
undetectable		 2kotA-1igoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 8 VAL A 116
THR A 115
PHE A 114
THR A 113
 None
 0.94A 2kotB-1igoA:
undetectable		 2kotB-1igoA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 8 LEU A 180
PHE A  36
ALA A 191
ALA A  38
 None
 0.84A 3ax9B-1igoA:
undetectable		 3ax9B-1igoA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 7 SER A  80
LYS A  21
LEU A  19
ALA A  46
 None
 1.04A 3cfqA-1igoA:
undetectable
3cfqB-1igoA:
undetectable		 3cfqA-1igoA:
20.57
3cfqB-1igoA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		3 / 3 ASP A 117
PHE A 114
SER A 159
 None
 1.00A 3i5uB-1igoA:
undetectable		 3i5uB-1igoA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 12 GLY A  86
ILE A  66
GLY A  51
VAL A 156
VAL A 158
 None
 0.97A 3ucbA-1igoA:
undetectable		 3ucbA-1igoA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 12 GLY A  86
ILE A  66
GLY A  51
VAL A 156
VAL A 158
 None
 0.97A 3ucbB-1igoA:
undetectable		 3ucbB-1igoA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 8 TYR A  81
TRP A 144
THR A 107
TYR A 104
 None
 1.49A 3wipB-1igoA:
undetectable
3wipC-1igoA:
undetectable		 3wipB-1igoA:
22.75
3wipC-1igoA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 7 PHE A  54
GLY A  51
THR A 178
ILE A  66
 None
 0.91A 4ejjA-1igoA:
0.0		 4ejjA-1igoA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		3 / 3 LYS A  21
LEU A  19
ALA A  46
 None
 0.64A 4iizA-1igoA:
0.0		 4iizA-1igoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		3 / 3 LYS A  21
LEU A  19
ALA A  46
 None
 0.64A 4ikiA-1igoA:
0.3		 4ikiA-1igoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 7 LYS A  21
LEU A  19
ALA A  46
SER A  80
 None
 0.94A 4iklA-1igoA:
0.3
4iklB-1igoA:
undetectable		 4iklA-1igoA:
22.01
4iklB-1igoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 5 ILE A  97
VAL A 156
VAL A  84
THR A 178
 None
 0.74A 4xdtA-1igoA:
0.1		 4xdtA-1igoA:
22.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 8 THR A 107
THR A 126
ARG A 128
GLN A 142
 None
 1.06A 5tzoA-1igoA:
25.2		 5tzoA-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 8 TYR A 124
THR A 126
ARG A 128
GLN A 142
TRP A 144
 None
 0.73A 5tzoA-1igoA:
25.2		 5tzoA-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 12 TRP A  87
TYR A  96
PRO A 132
TRP A 144
GLY A 184
 None
 0.63A 5tzoA-1igoA:
25.2		 5tzoA-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		3 / 3 ARG A 128
PRO A 132
TYR A 185
 None
 0.81A 5tzoB-1igoA:
25.2		 5tzoB-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 8 THR A 109
ARG A 128
GLN A 142
TRP A 144
 None
 1.34A 5tzoB-1igoA:
25.2		 5tzoB-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 8 TYR A 124
THR A 126
ARG A 128
GLN A 142
TRP A 144
 None
 0.64A 5tzoB-1igoA:
25.2		 5tzoB-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 12 TRP A  87
TYR A  96
PRO A 132
TRP A 144
GLY A 184
 None
 0.65A 5tzoC-1igoA:
25.2		 5tzoC-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		4 / 8 THR A 109
ARG A 128
GLN A 142
TRP A 144
 None
 1.38A 5tzoC-1igoA:
25.2		 5tzoC-1igoA:
48.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 8 TYR A 124
THR A 126
ARG A 128
GLN A 142
TRP A 144
 None
 0.65A 5tzoC-1igoA:
25.2		 5tzoC-1igoA:
48.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 1igo FAMILY 11 XYLANASE
(Bacillus
subtilis) 		5 / 12 ALA A 191
THR A   3
PHE A  48
VAL A 182
TYR A  70
 None
 1.32A 6hu9N-1igoA:
0.0		 6hu9N-1igoA:
19.12