SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ihm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 5 LEU A1470
SER A1240
LEU A1241
GLY A1499
 None
 1.01A 1a4lB-1ihmA:
undetectable		 1a4lB-1ihmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 4 ILE A1149
LEU A1182
VAL A1160
ILE A1158
 None
 0.89A 1fm6D-1ihmA:
undetectable		 1fm6D-1ihmA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 SER A1244
PHE A1421
LEU A1481
LEU A1233
 None
 0.99A 2bfpA-1ihmA:
undetectable		 2bfpA-1ihmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 SER A1244
PHE A1421
LEU A1481
LEU A1233
 None
 0.98A 2bfpB-1ihmA:
undetectable		 2bfpB-1ihmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 SER A1244
PHE A1421
LEU A1481
LEU A1233
 None
 0.99A 2bfpD-1ihmA:
undetectable		 2bfpD-1ihmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 9 LEU A1437
LEU A1233
LEU A1459
ALA A1457
PHE A1231
 None
 1.24A 2vcvD-1ihmA:
undetectable		 2vcvD-1ihmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 9 LEU A1437
LEU A1233
LEU A1459
ALA A1457
PHE A1231
 None
 1.21A 2vcvE-1ihmA:
0.0		 2vcvE-1ihmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 9 LEU A1437
LEU A1233
LEU A1459
ALA A1457
PHE A1231
 None
 1.21A 2vcvH-1ihmA:
0.0		 2vcvH-1ihmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 9 LEU A1437
LEU A1233
LEU A1459
ALA A1457
PHE A1231
 None
 1.21A 2vcvI-1ihmA:
undetectable		 2vcvI-1ihmA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 LEU A1113
ILE A1123
ILE A1128
LEU A1162
 None
 0.89A 2xkwB-1ihmA:
undetectable		 2xkwB-1ihmA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 12 MET A1332
ILE A1330
LEU A1356
GLU A1313
GLU A1303
 None
 1.37A 3aocC-1ihmA:
0.0		 3aocC-1ihmA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		3 / 3 GLY A1296
GLY A1367
GLY A1365
 None
 0.41A 3bogC-1ihmA:
undetectable		 3bogC-1ihmA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 GLY A1363
TYR A1343
GLY A1365
ASN A1362
 None
 0.96A 3e9rA-1ihmA:
undetectable		 3e9rA-1ihmA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 GLY A1363
TYR A1343
GLY A1365
ASN A1362
 None
 0.95A 3e9rC-1ihmA:
undetectable		 3e9rC-1ihmA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 THR A1119
GLY A1121
LEU A1190
ILE A1070
 None
 0.93A 3nbqC-1ihmA:
0.0		 3nbqC-1ihmA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 7 LEU A1272
ARG A1269
PRO A1412
VAL A1409
 None
 1.12A 4klrA-1ihmA:
undetectable		 4klrA-1ihmA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 GLU A1472
ARG A1205
GLU A1067
SER A1505
 None
 1.16A 4kr3A-1ihmA:
undetectable		 4kr3A-1ihmA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 5 LEU A1418
SER A1262
LEU A1436
ASN A1259
 None
 1.23A 4n09B-1ihmA:
undetectable		 4n09B-1ihmA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 11 LEU A1373
ALA A1246
PRO A1247
VAL A1287
THR A1280
 None
 1.33A 4uuuB-1ihmA:
0.0		 4uuuB-1ihmA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 GLY A1115
THR A1119
LEU A1190
LEU A1186
 None
 0.88A 5hs1A-1ihmA:
undetectable		 5hs1A-1ihmA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1ihm CAPSID PROTEIN
(Norwalk
virus) 		5 / 12 LEU A1437
TRP A1506
PHE A1231
PHE A1503
LEU A1445
 None
 1.42A 6a93A-1ihmA:
undetectable		 6a93A-1ihmA:
21.79