SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ihp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		3 / 3 GLU A 112
TYR A  15
PHE A 108
 None
 0.87A 1eqbB-1ihpA:
undetectable		 1eqbB-1ihpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		3 / 3 GLU A 112
TYR A  15
PHE A 108
 None
 0.86A 1eqbA-1ihpA:
undetectable		 1eqbA-1ihpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		3 / 3 GLU A 112
TYR A  15
PHE A 108
 None
 0.86A 1eqbD-1ihpA:
undetectable		 1eqbD-1ihpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		3 / 3 GLU A 112
TYR A  15
PHE A 108
 None
 0.86A 1eqbC-1ihpA:
undetectable		 1eqbC-1ihpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 LEU A 100
LEU A  75
ALA A  74
PHE A 258
LEU A 237
 None
 0.99A 1g5yB-1ihpA:
undetectable		 1g5yB-1ihpA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 LEU A 113
SER A 116
SER A 382
VAL A 143
LEU A 187
 None
 1.11A 1rk3A-1ihpA:
0.0		 1rk3A-1ihpA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.90A 1v55N-1ihpA:
0.0
1v55W-1ihpA:
0.0		 1v55N-1ihpA:
21.69
1v55W-1ihpA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 5 LEU A 113
GLY A  60
HIS A  59
PHE A  31
 None
 0.92A 1xf1A-1ihpA:
undetectable		 1xf1A-1ihpA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 6 LEU A 113
GLY A  60
HIS A  59
PHE A  31
 None
 0.90A 1xf1B-1ihpA:
undetectable		 1xf1B-1ihpA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 GLY A 289
LEU A 187
ASP A 188
ASP A 335
SER A 314
 None
 1.35A 2b9eA-1ihpA:
undetectable		 2b9eA-1ihpA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.93A 2einA-1ihpA:
0.0
2einJ-1ihpA:
0.0		 2einA-1ihpA:
21.69
2einJ-1ihpA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_A_DVAA35_0
(UBIQUITIN)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 4 GLN A 155
GLU A 152
ILE A 151
PRO A 171
 None
 1.15A 2fcnA-1ihpA:
undetectable		 2fcnA-1ihpA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 6 GLN A 155
GLU A 152
ILE A 151
PRO A 171
 None
 1.10A 2fcnA-1ihpA:
0.0
2fcnB-1ihpA:
0.0		 2fcnA-1ihpA:
10.21
2fcnB-1ihpA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 6 THR A  65
ASP A 103
SER A 140
VAL A 143
 None
 1.24A 2hdnI-1ihpA:
0.0
2hdnJ-1ihpA:
undetectable
2hdnL-1ihpA:
undetectable		 2hdnI-1ihpA:
8.84
2hdnJ-1ihpA:
21.88
2hdnL-1ihpA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 6 ILE A 177
LEU A 187
LEU A 319
ASP A 320
 None
 1.06A 2rlfA-1ihpA:
0.0
2rlfD-1ihpA:
undetectable		 2rlfA-1ihpA:
9.12
2rlfD-1ihpA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 LEU A 113
SER A 116
SER A 382
VAL A 143
LEU A 187
 None
 1.07A 2zlcA-1ihpA:
0.0		 2zlcA-1ihpA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.88A 3abmN-1ihpA:
0.0
3abmW-1ihpA:
0.0		 3abmN-1ihpA:
21.69
3abmW-1ihpA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 6 SER A 116
PHE A 120
TYR A 385
PRO A 133
 None
 1.46A 3jqaB-1ihpA:
undetectable		 3jqaB-1ihpA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 9 GLU A 299
GLN A  54
ARG A 136
ASP A 335
LEU A 349
 None
 1.41A 3mjrA-1ihpA:
0.0		 3mjrA-1ihpA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 ILE A 144
SER A 140
GLY A 139
GLU A 179
SER A 337
 None
 1.49A 3r75A-1ihpA:
undetectable		 3r75A-1ihpA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 ILE A 144
SER A 140
GLY A 139
GLU A 179
SER A 337
 None
 1.49A 3r75B-1ihpA:
undetectable		 3r75B-1ihpA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 LEU A 113
SER A 116
ARG A 383
SER A 382
LEU A 187
 None
 1.06A 3vt7A-1ihpA:
0.1		 3vt7A-1ihpA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1ihp PHYTASE
(Aspergillus
ficuum) 		3 / 3 TYR A 296
PHE A  52
ARG A 303
 None
 1.03A 4g19D-1ihpA:
0.0		 4g19D-1ihpA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 8 ASP A 239
ASP A 339
ARG A  58
GLU A 205
 None
 1.16A 4gkhF-1ihpA:
undetectable		 4gkhF-1ihpA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 PHE A  32
ALA A  29
THR A 367
SER A 275
LEU A  34
 None
 1.43A 4qztC-1ihpA:
0.0		 4qztC-1ihpA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 LEU A 113
HIS A 338
PRO A 379
LEU A 346
ILE A 342
 None
 1.25A 5dv4A-1ihpA:
undetectable		 5dv4A-1ihpA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 LEU A 346
SER A 382
VAL A 378
SER A 314
GLY A 190
 None
 1.36A 5f9zB-1ihpA:
undetectable		 5f9zB-1ihpA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 8 LEU A 261
PHE A 262
THR A 230
LEU A 229
 None
 0.91A 5zcpN-1ihpA:
0.0
5zcpW-1ihpA:
0.0		 5zcpN-1ihpA:
21.69
5zcpW-1ihpA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1ihp PHYTASE
(Aspergillus
ficuum) 		5 / 12 VAL A 408
VAL A  55
LEU A 384
GLY A 371
ASN A 404
 None
 1.11A 6drzA-1ihpA:
undetectable		 6drzA-1ihpA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1ihp PHYTASE
(Aspergillus
ficuum) 		4 / 8 TYR A 272
GLN A 368
ASN A 365
ILE A 366
 None
 1.06A 6hzpA-1ihpA:
1.1		 6hzpA-1ihpA:
22.20