SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iie'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 1.25A 2zj0A-1iieA:
undetectable		 2zj0A-1iieA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 1.23A 3ce6A-1iieA:
undetectable		 3ce6A-1iieA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 1.24A 3ce6C-1iieA:
undetectable		 3ce6C-1iieA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 1.01A 4lvcA-1iieA:
undetectable		 4lvcA-1iieA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 1.04A 4lvcC-1iieA:
undetectable		 4lvcC-1iieA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 0.98A 6gbnA-1iieA:
undetectable		 6gbnA-1iieA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 1iie PROTEIN (HLA-DR
ANTIGENS ASSOCIATED
INVARIANT CHAIN)
(Homo
sapiens) 		4 / 5 GLN A 131
THR A 156
HIS A 152
LEU A 142
 None
 0.95A 6gbnD-1iieA:
undetectable		 6gbnD-1iieA:
9.47