SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iio'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 1iio CONSERVED
HYPOTHETICAL PROTEIN
MTH865
(Methanothermobac
ter
thermautotrophic
us) 		6 / 11 THR A  40
ALA A  51
GLY A  37
ILE A  13
LEU A  17
ALA A  16
 None
 1.22A 3dcmX-1iioA:
undetectable		 3dcmX-1iioA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 1iio CONSERVED
HYPOTHETICAL PROTEIN
MTH865
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 ALA A  54
VAL A  76
LEU A  81
VAL A  71
ILE A  75
 None
 0.92A 6dgxB-1iioA:
undetectable		 6dgxB-1iioA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 1iio CONSERVED
HYPOTHETICAL PROTEIN
MTH865
(Methanothermobac
ter
thermautotrophic
us) 		5 / 10 ALA A  54
VAL A  76
ILE A   9
VAL A  71
ILE A  75
 None
 0.96A 6dj2A-1iioA:
undetectable		 6dj2A-1iioA:
24.72