SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 9 GLU A  96
GLY A  63
GLY A  94
GLY A  95
ASP A  86
 None
 1.20A 1mxdA-1iipA:
0.0		 1mxdA-1iipA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 ASP A 196
GLY A 199
ILE A 229
MET A 241
 None
 0.77A 1n13A-1iipA:
undetectable
1n13F-1iipA:
0.0		 1n13A-1iipA:
10.68
1n13F-1iipA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 11 THR A  62
GLY A  94
GLU A 101
SER A  88
ASN A  89
 None
 1.47A 1odiA-1iipA:
0.0		 1odiA-1iipA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 11 THR A  62
GLY A  94
GLU A 101
SER A  88
ASN A  89
 None
 1.44A 1odiC-1iipA:
undetectable		 1odiC-1iipA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 11 THR A  62
GLY A  94
GLU A 101
SER A  88
ASN A  89
 None
 1.49A 1odiD-1iipA:
undetectable		 1odiD-1iipA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.13A 1p7lD-1iipA:
undetectable		 1p7lD-1iipA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.16A 1rg9A-1iipA:
undetectable		 1rg9A-1iipA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.17A 1rg9B-1iipA:
undetectable		 1rg9B-1iipA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.19A 2obvA-1iipA:
undetectable		 2obvA-1iipA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.16A 2p02A-1iipA:
undetectable		 2p02A-1iipA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 ILE A 229
MET A 241
ASP A 196
GLY A 199
 None
 0.78A 2qqcH-1iipA:
0.0
2qqcK-1iipA:
undetectable		 2qqcH-1iipA:
14.86
2qqcK-1iipA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PHE A 149
VAL A  41
PHE A 103
ASN A 128
 None
 1.23A 2wekA-1iipA:
undetectable		 2wekA-1iipA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PHE A 149
VAL A  41
PHE A 103
ASN A 128
 None
 1.23A 2wekB-1iipA:
undetectable		 2wekB-1iipA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 6 THR A 139
SER A 119
LEU A 117
THR A 135
 None
 0.88A 3deuB-1iipA:
undetectable		 3deuB-1iipA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 11 PHE A 132
PHE A  48
PHE A  73
ILE A 178
LEU A  34
 None
 1.17A 3t3rA-1iipA:
0.0		 3t3rA-1iipA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
SER A 198
ASP A 200
 None
 1.03A 4k0bB-1iipA:
undetectable		 4k0bB-1iipA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 6 VAL A 152
ILE A 153
TRP A 190
LEU A 184
 None
 0.74A 4l1wB-1iipA:
undetectable		 4l1wB-1iipA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
SER A 198
ASP A 200
 None
 1.03A 4l7iB-1iipA:
undetectable		 4l7iB-1iipA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 7 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.19A 4ndnC-1iipA:
undetectable		 4ndnC-1iipA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 LEU A 162
VAL A 152
LEU A  34
ILE A 134
 None
 0.71A 4r38D-1iipA:
undetectable		 4r38D-1iipA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.13A 5a1iA-1iipA:
undetectable		 5a1iA-1iipA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 7 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.13A 5a1iA-1iipA:
undetectable		 5a1iA-1iipA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 12 GLY A 129
ILE A  98
ASN A 122
PHE A  48
LEU A 118
 None
 1.06A 5fa8A-1iipA:
undetectable		 5fa8A-1iipA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.09A 5t8sB-1iipA:
undetectable		 5t8sB-1iipA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 6 MET A  81
GLU A 170
GLY A  84
GLY A  85
 None
 0.97A 5x7pB-1iipA:
0.0		 5x7pB-1iipA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 5 TYR A 110
VAL A 148
LEU A 117
SER A  11
 None
 1.10A 6a7pA-1iipA:
4.3		 6a7pA-1iipA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		5 / 9 ILE A 161
LEU A 162
LYS A 160
ARG A  31
ASP A  21
 None
 1.34A 6c2mC-1iipA:
undetectable		 6c2mC-1iipA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 4 VAL A  33
GLY A 155
ASP A 208
ASP A 204
 None
None
None
GOL  A 371 (-3.8A)
 1.40A 6cjkC-1iipA:
undetectable		 6cjkC-1iipA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 4 VAL A 158
GLY A  30
ASP A  21
ASP A  23
 None
 1.43A 6cjkC-1iipA:
undetectable		 6cjkC-1iipA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.13A 6fbnB-1iipA:
undetectable		 6fbnB-1iipA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.14A 6fboA-1iipA:
undetectable		 6fboA-1iipA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 8 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.15A 6fcdA-1iipA:
undetectable		 6fcdA-1iipA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1iip CYCLOPHILIN 40
(Bos
taurus) 		4 / 7 PRO A 194
ASP A 196
PHE A 233
ASP A 200
 None
 1.13A 6g6rA-1iipA:
undetectable		 6g6rA-1iipA:
23.27