SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iiw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.20A 1m8eB-1iiwA:
0.0		 1m8eB-1iiwA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.16A 1nodB-1iiwA:
0.0		 1nodB-1iiwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.12A 1qomA-1iiwA:
0.0		 1qomA-1iiwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.78A 1rxcB-1iiwA:
undetectable		 1rxcB-1iiwA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.78A 1rxcE-1iiwA:
undetectable		 1rxcE-1iiwA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.80A 1rxcI-1iiwA:
undetectable		 1rxcI-1iiwA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.76A 1rxcK-1iiwA:
undetectable		 1rxcK-1iiwA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE A 192
TYR A  91
GLY A  29
VAL A  10
 None
 0.89A 1t88A-1iiwA:
undetectable		 1t88A-1iiwA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 MET A 160
VAL A 159
LEU A  98
PHE A 108
 None
 1.16A 1x8vA-1iiwA:
0.0		 1x8vA-1iiwA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A 102
THR A 103
ALA A 104
VAL A 156
 None
 0.81A 2a1hA-1iiwA:
undetectable
2a1hB-1iiwA:
undetectable		 2a1hA-1iiwA:
22.37
2a1hB-1iiwA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A 156
GLY A 102
THR A 103
ALA A 104
 None
 0.82A 2a1hA-1iiwA:
undetectable
2a1hB-1iiwA:
undetectable		 2a1hA-1iiwA:
22.37
2a1hB-1iiwA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 PHE A 192
TYR A  91
GLY A  29
VAL A  10
 None
 0.84A 2a1oA-1iiwA:
undetectable		 2a1oA-1iiwA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 9 PHE A 192
TYR A  91
GLY A  29
VAL A  10
ILE A  70
 None
 1.14A 2a1oB-1iiwA:
undetectable		 2a1oB-1iiwA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 MET A 208
VAL A 216
PHE A 220
THR A 221
 None
 1.15A 2kotA-1iiwA:
0.0		 2kotA-1iiwA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.13A 2nodB-1iiwA:
0.0		 2nodB-1iiwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.20A 3e6tB-1iiwA:
0.0		 3e6tB-1iiwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.05A 3e7iB-1iiwA:
0.0		 3e7iB-1iiwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 PRO A 189
TYR A 190
GLY A 191
THR A  88
 None
 1.50A 3ib0A-1iiwA:
7.8		 3ib0A-1iiwA:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 ILE A 183
VAL A 185
ARG A 163
LEU A 166
 None
 0.83A 3kp6A-1iiwA:
undetectable
3kp6B-1iiwA:
undetectable		 3kp6A-1iiwA:
20.80
3kp6B-1iiwA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 ILE A  73
VAL A 193
ILE A  68
ILE A  70
SER A  31
 None
 1.30A 3kpbD-1iiwA:
undetectable		 3kpbD-1iiwA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 VAL A  38
VAL A  34
TRP A  35
 None
 0.87A 3l8lA-1iiwA:
undetectable
3l8lB-1iiwA:
undetectable		 3l8lA-1iiwA:
10.26
3l8lB-1iiwA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 0.99A 3nw2A-1iiwA:
0.0		 3nw2A-1iiwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ARG A  36
ILE A  30
TRP A 224
 None
 1.06A 3nw2B-1iiwA:
0.0		 3nw2B-1iiwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.74A 4e1vA-1iiwA:
undetectable		 4e1vA-1iiwA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.76A 4e1vC-1iiwA:
undetectable		 4e1vC-1iiwA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.76A 4e1vD-1iiwA:
undetectable		 4e1vD-1iiwA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.73A 4e1vE-1iiwA:
undetectable		 4e1vE-1iiwA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.81A 4e1vG-1iiwA:
undetectable		 4e1vG-1iiwA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 THR A 181
GLY A  97
ILE A 183
VAL A 185
 None
 0.79A 4e1vH-1iiwA:
undetectable		 4e1vH-1iiwA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 1iiw SLR1257 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 ILE A  73
PHE A  87
ARG A  79
ILE A  58
 None
 1.39A 4zzcB-1iiwA:
undetectable
4zzcC-1iiwA:
0.0		 4zzcB-1iiwA:
22.46
4zzcC-1iiwA:
22.46