SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ij5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
3 / 3 ARG A 108
ARG A 103
ARG A 227
None
0.91A 1l7fA-1ij5A:
undetectable
1l7fA-1ij5A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
3 / 3 ARG A 108
ARG A 103
ARG A 227
None
0.91A 1l7hA-1ij5A:
undetectable
1l7hA-1ij5A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 VAL A 348
LEU A 195
PHE A 196
LEU A 180
HIS A 279
None
1.41A 1mmkA-1ij5A:
undetectable
1mmkA-1ij5A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.16A 1t88B-1ij5A:
0.0
1t88B-1ij5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 LEU A 347
ALA A 314
ILE A 316
ILE A 187
PHE A 352
None
0.97A 2h42C-1ij5A:
0.1
2h42C-1ij5A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.17A 2m56A-1ij5A:
0.0
2m56A-1ij5A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 LEU A 311
ALA A 314
ILE A 316
ILE A 187
PHE A 352
None
0.91A 3b2rA-1ij5A:
2.5
3b2rA-1ij5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 11 LEU A 311
ALA A 314
ILE A 316
ILE A 187
PHE A 352
None
0.89A 3b2rB-1ij5A:
undetectable
3b2rB-1ij5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.46A 3b7eA-1ij5A:
undetectable
3b7eA-1ij5A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.46A 3b7eB-1ij5A:
undetectable
3b7eB-1ij5A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.10A 3fwgA-1ij5A:
0.0
3fwgA-1ij5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 7 LEU A 156
VAL A 223
LEU A 176
LEU A 349
None
0.73A 3g8iA-1ij5A:
0.0
3g8iA-1ij5A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 ASP A 101
SER A 168
ILE A  34
SER A  36
LEU A  39
None
1.00A 3k2hB-1ij5A:
undetectable
3k2hB-1ij5A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 11 ASP A 252
LEU A 339
SER A 340
PHE A 344
GLU A 343
None
1.04A 3ko0A-1ij5A:
7.4
3ko0B-1ij5A:
7.1
3ko0C-1ij5A:
7.1
3ko0D-1ij5A:
7.1
3ko0A-1ij5A:
17.12
3ko0B-1ij5A:
17.12
3ko0C-1ij5A:
17.12
3ko0D-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 11 GLU A 343
LEU A 339
SER A 340
PHE A 344
ASP A 252
None
1.06A 3ko0C-1ij5A:
7.1
3ko0D-1ij5A:
7.1
3ko0E-1ij5A:
6.9
3ko0F-1ij5A:
7.4
3ko0C-1ij5A:
17.12
3ko0D-1ij5A:
17.12
3ko0E-1ij5A:
17.12
3ko0F-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 11 ASP A 252
LEU A 339
SER A 340
PHE A 344
GLU A 343
None
1.11A 3ko0C-1ij5A:
7.1
3ko0D-1ij5A:
7.1
3ko0E-1ij5A:
6.9
3ko0F-1ij5A:
7.4
3ko0C-1ij5A:
17.12
3ko0D-1ij5A:
17.12
3ko0E-1ij5A:
17.12
3ko0F-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 11 GLU A 343
LEU A 339
SER A 340
PHE A 344
ASP A 252
None
0.98A 3ko0E-1ij5A:
6.9
3ko0F-1ij5A:
7.4
3ko0G-1ij5A:
6.8
3ko0H-1ij5A:
7.2
3ko0E-1ij5A:
17.12
3ko0F-1ij5A:
17.12
3ko0G-1ij5A:
17.12
3ko0H-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 343
LEU A 339
SER A 340
PHE A 344
ASP A 252
None
1.08A 3ko0G-1ij5A:
6.8
3ko0H-1ij5A:
7.2
3ko0I-1ij5A:
6.8
3ko0J-1ij5A:
6.9
3ko0G-1ij5A:
17.12
3ko0H-1ij5A:
17.12
3ko0I-1ij5A:
17.12
3ko0J-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 LEU A 339
SER A 340
PHE A 344
GLU A 343
ASP A 252
None
1.08A 3ko0K-1ij5A:
7.0
3ko0L-1ij5A:
7.3
3ko0S-1ij5A:
6.9
3ko0T-1ij5A:
7.3
3ko0K-1ij5A:
17.12
3ko0L-1ij5A:
17.12
3ko0S-1ij5A:
17.12
3ko0T-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 343
LEU A 339
SER A 340
PHE A 344
ASP A 252
None
1.05A 3ko0K-1ij5A:
7.0
3ko0L-1ij5A:
7.3
3ko0M-1ij5A:
7.1
3ko0N-1ij5A:
7.3
3ko0K-1ij5A:
17.12
3ko0L-1ij5A:
17.12
3ko0M-1ij5A:
17.12
3ko0N-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 LEU A 339
SER A 340
PHE A 344
GLU A 343
ASP A 252
None
1.02A 3ko0M-1ij5A:
7.1
3ko0N-1ij5A:
7.3
3ko0O-1ij5A:
7.1
3ko0P-1ij5A:
7.1
3ko0M-1ij5A:
17.12
3ko0N-1ij5A:
17.12
3ko0O-1ij5A:
17.12
3ko0P-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 11 ASP A 252
GLU A 343
LEU A 339
SER A 340
PHE A 344
None
1.13A 3ko0K-1ij5A:
7.0
3ko0L-1ij5A:
7.3
3ko0M-1ij5A:
7.1
3ko0N-1ij5A:
7.3
3ko0K-1ij5A:
17.12
3ko0L-1ij5A:
17.12
3ko0M-1ij5A:
17.12
3ko0N-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 ASP A 252
GLU A 343
LEU A 339
SER A 340
PHE A 344
None
1.04A 3ko0M-1ij5A:
7.1
3ko0N-1ij5A:
7.3
3ko0O-1ij5A:
7.1
3ko0P-1ij5A:
7.0
3ko0M-1ij5A:
17.12
3ko0N-1ij5A:
17.12
3ko0O-1ij5A:
17.12
3ko0P-1ij5A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 7 VAL A 179
LEU A 148
PHE A 160
LEU A 161
None
1.02A 3qeoB-1ij5A:
undetectable
3qeoB-1ij5A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.45A 3ti5A-1ij5A:
undetectable
3ti5A-1ij5A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.46A 3ti5B-1ij5A:
undetectable
3ti5B-1ij5A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.12A 3wrhE-1ij5A:
0.0
3wrhE-1ij5A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.12A 3wrjE-1ij5A:
0.0
3wrjE-1ij5A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 ASP A 230
THR A 236
LEU A 237
GLU A 241
None
1.48A 4a3pA-1ij5A:
undetectable
4a3pA-1ij5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 THR A  63
LEU A  60
GLU A  75
LYS A  72
None
1.43A 4a3pA-1ij5A:
undetectable
4a3pA-1ij5A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
3 / 3 ARG A 105
ASP A 175
GLN A 174
None
0.87A 4azsA-1ij5A:
undetectable
4azsA-1ij5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.41A 4b7nA-1ij5A:
undetectable
4b7nA-1ij5A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.35A 4b7qA-1ij5A:
undetectable
4b7qA-1ij5A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.49A 4b7qB-1ij5A:
undetectable
4b7qB-1ij5A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 12 GLU A 120
SER A 163
GLU A 107
GLU A 111
ARG A 108
None
1.45A 4b7qC-1ij5A:
undetectable
4b7qC-1ij5A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.07A 4ek1A-1ij5A:
0.0
4ek1A-1ij5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.11A 4g3rA-1ij5A:
0.0
4g3rA-1ij5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.09A 4kkyX-1ij5A:
0.0
4kkyX-1ij5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.14A 4l49A-1ij5A:
0.0
4l49A-1ij5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 6 PHE A 344
LEU A 311
VAL A 310
VAL A 286
None
1.05A 4l4cA-1ij5A:
0.0
4l4cA-1ij5A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
5 / 9 VAL A 348
LEU A 222
LEU A 290
LEU A 285
ILE A 289
None
1.25A 4ubsA-1ij5A:
1.1
4ubsA-1ij5A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
3 / 3 ARG A  42
LYS A  88
GLU A  91
None
0.82A 5d0yA-1ij5A:
0.0
5d0yA-1ij5A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 GLN A 178
THR A 186
HIS A 279
LEU A 156
None
1.24A 6aphA-1ij5A:
undetectable
6aphA-1ij5A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)
1ij5 PLASMODIAL SPECIFIC
LAV1-2 PROTEIN

(Physarum
polycephalum)
4 / 5 GLN A 178
THR A 186
HIS A 279
LEU A 156
None
1.31A 6gbnB-1ij5A:
undetectable
6gbnB-1ij5A:
22.20