SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ij9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 12 MET A  58
LEU A  21
ILE A  88
ALA A  13
TYR A  69
 None
 1.19A 2japA-1ij9A:
undetectable		 2japA-1ij9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 12 MET A  58
LEU A  21
ILE A  88
ALA A  13
TYR A  69
 None
 1.20A 2japB-1ij9A:
undetectable		 2japB-1ij9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 12 MET A  58
LEU A  21
ILE A  88
ALA A  13
TYR A  69
 None
 1.19A 2japC-1ij9A:
undetectable		 2japC-1ij9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 12 MET A  58
LEU A  21
ILE A  88
ALA A  13
TYR A  69
 None
 1.22A 2japD-1ij9A:
undetectable		 2japD-1ij9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		4 / 5 ILE A 109
MET A 135
LEU A 193
LEU A 169
 None
 1.14A 2zb7A-1ij9A:
undetectable		 2zb7A-1ij9A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		6 / 12 LEU A 169
ALA A 189
ASP A  94
ILE A 126
VAL A 111
ILE A  97
 None
 1.32A 3jw2B-1ij9A:
undetectable		 3jw2B-1ij9A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 6 VAL A 118
SER A 114
ILE A  97
ALA A 173
LEU A 124
 None
 1.30A 3kk6B-1ij9A:
undetectable		 3kk6B-1ij9A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 11 LEU A 169
ALA A 189
ASP A  94
VAL A 111
ILE A  97
 None
 0.98A 3oxxD-1ij9A:
undetectable		 3oxxD-1ij9A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		3 / 3 THR A  72
SER A  34
ARG A  36
 None
 0.82A 3phnA-1ij9A:
0.0		 3phnA-1ij9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		6 / 10 LEU A 169
ALA A 189
ASP A  94
ILE A 126
VAL A 111
ILE A  97
 None
 1.29A 4dqfB-1ij9A:
undetectable		 4dqfB-1ij9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 128
GLU A 163
GLY A 131
LEU A 103
ILE A  97
 None
 1.20A 4hytA-1ij9A:
undetectable		 4hytA-1ij9A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 128
GLU A 163
GLY A 131
LEU A 103
ILE A  97
 None
 1.20A 4hytC-1ij9A:
0.0		 4hytC-1ij9A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		6 / 12 LEU A 169
ALA A 189
ASP A  94
ILE A 126
VAL A 111
ILE A  97
 None
 1.30A 4jecA-1ij9A:
undetectable		 4jecA-1ij9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		5 / 8 VAL A 195
LEU A 193
ILE A  97
VAL A 156
THR A 157
 None
 1.33A 4ma7A-1ij9A:
undetectable		 4ma7A-1ij9A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1ij9 VASCULAR CELL
ADHESION PROTEIN 1
(Homo
sapiens) 		4 / 4 LEU A 175
ASP A 122
PRO A 120
ARG A 123
 None
 1.38A 6fgdA-1ij9A:
undetectable		 6fgdA-1ij9A:
21.71