SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ijq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		5 / 10 THR A 413
LEU A 380
VAL A 632
THR A 638
VAL A 415
 None
 1.37A 1o76A-1ijqA:
0.0		 1o76A-1ijqA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		4 / 7 LEU A 578
ILE A 564
ALA A 610
ILE A 607
 None
 0.66A 1oniB-1ijqA:
undetectable
1oniC-1ijqA:
0.0		 1oniB-1ijqA:
18.37
1oniC-1ijqA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		5 / 12 LEU A 554
ASP A 568
VAL A 569
GLY A 572
TYR A 532
 None
 1.37A 3hgiA-1ijqA:
undetectable		 3hgiA-1ijqA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		3 / 3 TYR A 511
MET A 510
ILE A 467
 None
 0.74A 4c8bB-1ijqA:
undetectable		 4c8bB-1ijqA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		3 / 3 SER A 589
ALA A 591
VAL A 592
 None
 0.62A 4x20C-1ijqA:
undetectable		 4x20C-1ijqA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		5 / 9 THR A 413
LEU A 380
VAL A 632
THR A 638
VAL A 415
 None
 1.35A 5cp4A-1ijqA:
0.0		 5cp4A-1ijqA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		3 / 3 TRP A 599
ARG A 583
LEU A 621
 None
 0.98A 5dbyA-1ijqA:
undetectable		 5dbyA-1ijqA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		5 / 11 ASP A 481
THR A 482
VAL A 460
VAL A 503
MET A 510
 None
 1.46A 5jkwA-1ijqA:
0.0		 5jkwA-1ijqA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 1ijq LOW-DENSITY
LIPOPROTEIN RECEPTOR
(Homo
sapiens) 		4 / 6 LEU A 425
ALA A 454
SER A 423
ASN A 543
 None
 0.84A 6f88B-1ijqA:
0.0		 6f88B-1ijqA:
13.97