SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ijt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 1ijt FIBROBLAST GROWTH
FACTOR 4
(Homo
sapiens) 		4 / 7 GLU A 159
ARG A 123
GLU A 122
PRO A 120
 None
 1.37A 3ql6A-1ijtA:
undetectable		 3ql6A-1ijtA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 1ijt FIBROBLAST GROWTH
FACTOR 4
(Homo
sapiens) 		5 / 9 SER A 194
ALA A 168
VAL A 199
ALA A 180
GLY A 190
 None
 1.15A 6bklA-1ijtA:
undetectable
6bklB-1ijtA:
undetectable
6bklC-1ijtA:
undetectable
6bklD-1ijtA:
undetectable		 6bklA-1ijtA:
10.94
6bklB-1ijtA:
10.94
6bklC-1ijtA:
10.94
6bklD-1ijtA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 1ijt FIBROBLAST GROWTH
FACTOR 4
(Homo
sapiens) 		5 / 12 PHE A 135
GLY A 102
LEU A 115
GLY A 130
SER A 133
 None
 1.01A 6c2mA-1ijtA:
0.0		 6c2mA-1ijtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 1ijt FIBROBLAST GROWTH
FACTOR 4
(Homo
sapiens) 		4 / 8 GLY A 105
GLN A  97
PHE A 202
TYR A  87
 None
 1.15A 6eqpA-1ijtA:
undetectable		 6eqpA-1ijtA:
14.84