SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ijx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		5 / 11 ILE A 116
ALA A  83
ARG A  82
ASP A  51
PHE A  54
 None
 1.25A 2noaB-1ijxA:
undetectable		 2noaB-1ijxA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		5 / 12 MET A  37
TYR A  60
PHE A  40
ALA A  83
PHE A  55
 None
 1.38A 2vppA-1ijxA:
undetectable		 2vppA-1ijxA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		5 / 12 MET A  37
TYR A  60
PHE A  40
ALA A  83
PHE A  55
 None
 1.36A 2vppB-1ijxA:
undetectable		 2vppB-1ijxA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		4 / 5 LEU A  10
GLN A  39
LEU A  44
GLU A  41
 None
 1.10A 3h5gA-1ijxA:
undetectable
3h5gB-1ijxA:
undetectable		 3h5gA-1ijxA:
10.24
3h5gB-1ijxA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		5 / 12 MET A  37
TYR A  60
PHE A  40
ALA A  83
PHE A  55
 None
 1.27A 3hp1A-1ijxA:
undetectable		 3hp1A-1ijxA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		4 / 8 SER A  78
VAL A  79
VAL A 114
GLY A 113
 None
 0.99A 4mk4A-1ijxA:
undetectable		 4mk4A-1ijxA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ijx SECRETED
FRIZZLED-RELATED
SEQUENCE PROTEIN 3
(Mus
musculus) 		4 / 8 VAL A  79
ARG A  82
VAL A 114
GLY A 113
 None
 0.94A 4mk4A-1ijxA:
undetectable		 4mk4A-1ijxA:
14.83