SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ikf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 TRP H 112
PHE H  50
TRP H  47
 None
 1.18A 1r15C-1ikfH:
undetectable		 1r15C-1ikfH:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 TRP H 112
PHE H  50
TRP H  47
 None
 1.15A 1r15F-1ikfH:
undetectable		 1r15F-1ikfH:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 TRP H 112
PHE H  50
TRP H  47
 None
 1.16A 1r15G-1ikfH:
undetectable		 1r15G-1ikfH:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 TRP H 112
PHE H  50
TRP H  47
 None
 1.16A 1r15H-1ikfH:
undetectable		 1r15H-1ikfH:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.17A 1v55C-1ikfH:
undetectable
1v55N-1ikfH:
undetectable
1v55P-1ikfH:
undetectable		 1v55C-1ikfH:
21.91
1v55N-1ikfH:
17.73
1v55P-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 THR H 130
PRO H 160
PRO H 131
 None
 0.89A 2d55C-1ikfH:
undetectable		 2d55C-1ikfH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 5 TYR H  95
MET H  93
THR H 120
LEU H 121
 None
 1.44A 2eimW-1ikfH:
undetectable		 2eimW-1ikfH:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 ASP H 103
THR H 104
TYR H 109
LEU H 101
 None
 1.18A 3ablA-1ikfH:
undetectable
3ablC-1ikfH:
undetectable
3ablP-1ikfH:
undetectable		 3ablA-1ikfH:
17.73
3ablC-1ikfH:
21.91
3ablP-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 5 TYR H  95
MET H  93
THR H 120
LEU H 121
 None
 1.45A 3ag4J-1ikfH:
undetectable		 3ag4J-1ikfH:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.20A 3asoC-1ikfH:
undetectable
3asoN-1ikfH:
undetectable
3asoP-1ikfH:
undetectable		 3asoC-1ikfH:
21.91
3asoN-1ikfH:
17.73
3asoP-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 ASP H 103
THR H 104
TYR H 109
LEU H 101
 None
 1.10A 5b1bA-1ikfH:
undetectable
5b1bC-1ikfH:
undetectable
5b1bP-1ikfH:
undetectable		 5b1bA-1ikfH:
17.73
5b1bC-1ikfH:
21.91
5b1bP-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 ALA H  92
THR H  91
VAL H 122
GLU H  89
 None
 0.73A 5ecmD-1ikfH:
0.0		 5ecmD-1ikfH:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 ALA H  92
THR H  91
VAL H 122
GLU H  89
 None
 0.83A 5ecoD-1ikfH:
0.0		 5ecoD-1ikfH:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 SER H  88
LEU H  81
MET H  83
 None
 0.88A 5ikrB-1ikfH:
undetectable		 5ikrB-1ikfH:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.17A 5iy5C-1ikfH:
undetectable
5iy5N-1ikfH:
undetectable
5iy5P-1ikfH:
undetectable		 5iy5C-1ikfH:
22.26
5iy5N-1ikfH:
17.73
5iy5P-1ikfH:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		5 / 5 SER H 125
ALA H 127
PHE H 159
LEU H 183
ASP H 186
 None
 0.45A 5mthA-1ikfH:
26.8		 5mthA-1ikfH:
68.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.18A 5w97C-1ikfH:
undetectable
5w97a-1ikfH:
undetectable
5w97c-1ikfH:
undetectable		 5w97C-1ikfH:
21.91
5w97a-1ikfH:
17.73
5w97c-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.21A 5wauC-1ikfH:
undetectable
5waua-1ikfH:
undetectable
5wauc-1ikfH:
undetectable		 5wauC-1ikfH:
21.91
5waua-1ikfH:
17.73
5wauc-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 ASP H 103
THR H 104
TYR H 109
LEU H 101
 None
 1.14A 5x1bA-1ikfH:
undetectable
5x1bC-1ikfH:
undetectable
5x1bP-1ikfH:
undetectable		 5x1bA-1ikfH:
17.73
5x1bC-1ikfH:
21.91
5x1bP-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 ASP H 103
THR H 104
TYR H 109
LEU H 101
 None
 1.20A 5x1fA-1ikfH:
undetectable
5x1fC-1ikfH:
undetectable
5x1fP-1ikfH:
undetectable		 5x1fA-1ikfH:
17.73
5x1fC-1ikfH:
21.91
5x1fP-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.20A 5xdxC-1ikfH:
undetectable
5xdxN-1ikfH:
undetectable
5xdxP-1ikfH:
undetectable		 5xdxC-1ikfH:
21.71
5xdxN-1ikfH:
17.73
5xdxP-1ikfH:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.23A 5z84C-1ikfH:
undetectable
5z84N-1ikfH:
undetectable
5z84P-1ikfH:
undetectable		 5z84C-1ikfH:
21.91
5z84N-1ikfH:
17.73
5z84P-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		3 / 3 PRO H 197
SER H 198
SER H 199
 None
 0.70A 6bpyA-1ikfH:
undetectable		 6bpyA-1ikfH:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 8 LEU H 101
ASP H 103
THR H 104
TYR H 109
 None
 1.16A 6nknC-1ikfH:
undetectable
6nknN-1ikfH:
undetectable
6nknP-1ikfH:
undetectable		 6nknC-1ikfH:
21.91
6nknN-1ikfH:
17.73
6nknP-1ikfH:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ikf IGG1-KAPPA R45-45-11
FAB (HEAVY CHAIN)
(Homo
sapiens) 		4 / 7 ASP H 103
THR H 104
TYR H 109
LEU H 101
 None
 1.16A 6nmfA-1ikfH:
undetectable
6nmfC-1ikfH:
undetectable
6nmfP-1ikfH:
undetectable		 6nmfA-1ikfH:
17.73
6nmfC-1ikfH:
21.91
6nmfP-1ikfH:
21.91