SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1il1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 124
PRO A 126
THR A 125
PRO A 155
 None
 1.35A 1dsdC-1il1A:
undetectable		 1dsdC-1il1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 125
PRO A 155
THR A 124
PRO A 126
 None
 1.32A 1dsdC-1il1A:
undetectable		 1dsdC-1il1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 124
PRO A 126
THR A 125
PRO A 155
 None
 1.35A 1dsdC-1il1A:
undetectable		 1dsdC-1il1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		4 / 4 THR A 125
PRO A 155
THR A 124
PRO A 126
 None
 1.32A 1dsdC-1il1A:
undetectable		 1dsdC-1il1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B504_1
(HOMOSPERMIDINE
SYNTHASE)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		5 / 12 ALA A 209
PRO A 208
TYR A 153
TYR A 183
THR A 118
 None
 1.41A 4xqeB-1il1A:
undetectable		 4xqeB-1il1A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XRG_B_AG2B502_1
(HOMOSPERMIDINE
SYNTHASE)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		5 / 12 ALA A 209
PRO A 208
TYR A 153
TYR A 183
THR A 118
 None
 1.42A 4xrgB-1il1A:
undetectable		 4xrgB-1il1A:
18.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		5 / 5 SER A 120
ALA A 122
PHE A 154
LEU A 178
ASP A 181
 None
 0.42A 5mthA-1il1A:
19.4		 5mthA-1il1A:
79.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1il1 MONOCLONAL ANTIBODY
G3-519 (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 SER A 211
ALA A 206
VAL A 205
 None
 0.53A 5xiwC-1il1A:
undetectable		 5xiwC-1il1A:
13.51