SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1im3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1im3 CYTOMEGALOVIRUS
PROTEIN US2
(Human
betaherpesvirus
5) 		5 / 12 LEU D 131
LEU D 120
VAL D  89
LEU D 102
ILE D 129
 None
 1.12A 1s9pA-1im3D:
undetectable		 1s9pA-1im3D:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1im3 CYTOMEGALOVIRUS
PROTEIN US2
(Human
betaherpesvirus
5) 		5 / 12 LEU D 131
LEU D 120
VAL D  89
LEU D 102
ILE D 129
 None
 1.15A 1s9pD-1im3D:
undetectable		 1s9pD-1im3D:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 1im3 CYTOMEGALOVIRUS
PROTEIN US2
(Human
betaherpesvirus
5) 		4 / 4 GLU D 136
ARG D  51
ASN D  50
ASP D  49
 None
 1.42A 2zq9A-1im3D:
0.0		 2zq9A-1im3D:
18.33