SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1im9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		3 / 3 ARG D 148
GLY D 167
PRO D 168
 None
 0.72A 2hreD-1im9D:
0.0		 2hreD-1im9D:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		5 / 10 ILE D 102
LEU D  97
LEU D  17
GLY D  15
ALA D  12
 None
 1.17A 2xf3A-1im9D:
0.0		 2xf3A-1im9D:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		3 / 3 ASP D 163
PHE D 164
LEU D 166
 None
 0.67A 2zi9A-1im9D:
undetectable		 2zi9A-1im9D:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		3 / 3 PRO D  16
LEU D  17
ARG D 176
 None
 0.90A 3aqiA-1im9D:
undetectable		 3aqiA-1im9D:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		4 / 5 TYR D  80
LEU D  51
ASP D  47
VAL D  24
 None
 0.99A 4nkvA-1im9D:
undetectable		 4nkvA-1im9D:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		3 / 3 LEU D  97
LEU D  49
ASN D  63
 None
 0.70A 4otwA-1im9D:
undetectable		 4otwA-1im9D:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 1im9 KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL1
(Homo
sapiens) 		3 / 3 ASP D  98
ARG D  78
PRO D  96
 None
 1.00A 4wanC-1im9D:
undetectable		 4wanC-1im9D:
20.60