SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1imh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 1imh NUCLEAR FACTOR OF
ACTIVATED T CELLS 5
(Homo
sapiens) 		5 / 12 LEU C 193
THR C 289
VAL C 262
VAL C 255
GLY C 256
 None
 1.17A 3bf1A-1imhC:
undetectable
3bf1B-1imhC:
undetectable		 3bf1A-1imhC:
22.90
3bf1B-1imhC:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1imh NUCLEAR FACTOR OF
ACTIVATED T CELLS 5
(Homo
sapiens) 		3 / 3 GLN C 425
THR C 452
ASN C 393
 None
 0.68A 3v4tE-1imhC:
undetectable		 3v4tE-1imhC:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 1imh NUCLEAR FACTOR OF
ACTIVATED T CELLS 5
(Homo
sapiens) 		5 / 12 VAL C 255
ALA C 270
TYR C 268
VAL C 229
GLY C 310
 None
 1.33A 4mm6A-1imhC:
undetectable		 4mm6A-1imhC:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 1imh NUCLEAR FACTOR OF
ACTIVATED T CELLS 5
(Homo
sapiens) 		4 / 5 HIS C 216
ILE C 311
SER C 228
ALA C 270
 None
 1.18A 5msdA-1imhC:
undetectable		 5msdA-1imhC:
11.91