SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1imj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.11A 1dfoA-1imjA:
1.5		 1dfoA-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.11A 1dfoB-1imjA:
1.0		 1dfoB-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.12A 1dfoC-1imjA:
1.6		 1dfoC-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.12A 1dfoD-1imjA:
1.5		 1dfoD-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.12A 1eqbA-1imjA:
1.5		 1eqbA-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.12A 1eqbB-1imjA:
1.5		 1eqbB-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.13A 1eqbC-1imjA:
1.5		 1eqbC-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 LEU A  69
GLY A  71
SER A  75
ALA A  78
PHE A 120
 None
 1.12A 1eqbD-1imjA:
undetectable		 1eqbD-1imjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		4 / 8 PHE A  33
TYR A  62
LEU A 209
VAL A 106
 None
 0.89A 1fslA-1imjA:
undetectable		 1fslA-1imjA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		4 / 8 GLY A 201
LEU A 155
VAL A 134
MET A 183
 None
 1.01A 1gsfC-1imjA:
0.0		 1gsfC-1imjA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		4 / 5 LEU A 155
VAL A 157
ALA A 186
CYH A 190
 None
 1.07A 1mz9D-1imjA:
0.0		 1mz9D-1imjA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 11 ILE A  67
PHE A  21
ALA A  18
LEU A  19
VAL A  14
 None
 1.12A 4g1bB-1imjA:
4.4		 4g1bB-1imjA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 10 VAL A  96
VAL A  65
LEU A  36
GLY A  10
LEU A 100
 None
 1.06A 4ph9A-1imjA:
undetectable		 4ph9A-1imjA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 10 VAL A  96
VAL A  65
LEU A  36
GLY A  10
LEU A 100
 None
 1.07A 4ph9B-1imjA:
undetectable		 4ph9B-1imjA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 12 ILE A 108
GLY A 130
THR A 152
LEU A 175
PHE A 169
 None
 1.14A 4zdyA-1imjA:
undetectable		 4zdyA-1imjA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		5 / 9 ILE A 108
PHE A 205
GLY A 130
THR A 152
LEU A 172
 None
 1.16A 4ze0A-1imjA:
undetectable		 4ze0A-1imjA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1imj CCG1-INTERACTING
FACTOR B
(Homo
sapiens) 		4 / 6 LEU A  69
SER A 117
PRO A 119
PHE A 120
 None
 0.78A 5b8iA-1imjA:
undetectable		 5b8iA-1imjA:
17.93