SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1imv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASP A 156
VAL A 148
ILE A 122
VAL A 164
ILE A 160
 None
 0.90A 1fb7A-1imvA:
undetectable		 1fb7A-1imvA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 GLY A 195
LYS A 194
ASP A 394
GLY A 397
ARG A 396
 None
 1.03A 1sqfA-1imvA:
undetectable		 1sqfA-1imvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 LEU A  72
ALA A  68
ILE A  84
ALA A  76
PHE A 323
 None
 1.23A 2ejtA-1imvA:
undetectable		 2ejtA-1imvA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 9 GLY A 189
ILE A 160
THR A 150
VAL A 123
ILE A 183
 None
 1.36A 2nnhB-1imvA:
0.0		 2nnhB-1imvA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASN A  32
LEU A  34
ALA A  35
LEU A 106
PHE A  26
 None
 1.27A 2oaxB-1imvA:
undetectable		 2oaxB-1imvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASN A  32
LEU A  34
ALA A  35
LEU A 106
PHE A  26
 None
 1.27A 2oaxD-1imvA:
undetectable		 2oaxD-1imvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASN A  32
LEU A  34
ALA A  35
LEU A 106
PHE A  26
 None
 1.28A 2oaxE-1imvA:
undetectable		 2oaxE-1imvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASN A  32
LEU A  34
ALA A  35
LEU A 387
PHE A  26
 None
 1.38A 2oaxE-1imvA:
undetectable		 2oaxE-1imvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASN A  32
LEU A  34
ALA A  35
LEU A 106
PHE A  26
 None
 1.31A 2oaxF-1imvA:
undetectable		 2oaxF-1imvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 7 GLU A 104
ALA A 385
ASN A  32
ALA A  35
 None
 1.09A 2zgwA-1imvA:
undetectable		 2zgwA-1imvA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 6 GLU A 104
ALA A 385
ASN A  32
ALA A  35
 None
 1.08A 2zgwB-1imvA:
0.0		 2zgwB-1imvA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 7 VAL A 377
ILE A 243
GLY A 234
LEU A 366
 None
 0.85A 3bjwF-1imvA:
undetectable		 3bjwF-1imvA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ILE A 122
ALA A  68
GLU A 125
PRO A 180
LEU A 149
 None
 1.34A 3eigA-1imvA:
undetectable		 3eigA-1imvA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 4 ILE A 331
PHE A 124
ILE A 326
THR A 334
 None
 1.06A 3ia4A-1imvA:
undetectable		 3ia4A-1imvA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 11 ASP A 319
LEU A 314
ILE A  83
PHE A 323
SER A 184
 None
 1.26A 3ko0C-1imvA:
undetectable
3ko0D-1imvA:
undetectable
3ko0E-1imvA:
undetectable
3ko0F-1imvA:
undetectable		 3ko0C-1imvA:
13.28
3ko0D-1imvA:
13.28
3ko0E-1imvA:
13.28
3ko0F-1imvA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 11 SER A 184
PHE A 323
LEU A 314
ILE A  83
ASP A 319
 None
 1.27A 3ko0C-1imvA:
undetectable
3ko0D-1imvA:
undetectable
3ko0E-1imvA:
undetectable
3ko0F-1imvA:
undetectable		 3ko0C-1imvA:
13.28
3ko0D-1imvA:
13.28
3ko0E-1imvA:
13.28
3ko0F-1imvA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ASP A 319
LEU A 314
ILE A  83
PHE A 323
SER A 184
 None
 1.31A 3ko0G-1imvA:
undetectable
3ko0H-1imvA:
undetectable
3ko0I-1imvA:
undetectable
3ko0J-1imvA:
undetectable		 3ko0G-1imvA:
13.28
3ko0H-1imvA:
13.28
3ko0I-1imvA:
13.28
3ko0J-1imvA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 11 SER A 184
PHE A 323
ASP A 319
LEU A 314
ILE A  83
 None
 1.26A 3ko0A-1imvA:
undetectable
3ko0B-1imvA:
undetectable
3ko0I-1imvA:
undetectable
3ko0J-1imvA:
undetectable		 3ko0A-1imvA:
13.28
3ko0B-1imvA:
13.28
3ko0I-1imvA:
13.28
3ko0J-1imvA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ALA A 166
GLN A 165
LEU A 172
LEU A 188
THR A 144
 None
 1.47A 3vhuA-1imvA:
undetectable		 3vhuA-1imvA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 10 ILE A 331
PHE A 124
LEU A 138
ILE A 326
THR A 334
 None
 1.11A 4km0A-1imvA:
undetectable		 4km0A-1imvA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_B_CP6B201_1
(DIHYDROFOLATE
REDUCTASE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 ILE A 331
PHE A 124
LEU A 138
ILE A 326
THR A 334
 None
 1.12A 4km0B-1imvA:
undetectable		 4km0B-1imvA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 LEU A 370
ILE A 254
LEU A 246
ILE A 392
PRO A 395
 None
 0.87A 4odrA-1imvA:
undetectable
4odrB-1imvA:
undetectable		 4odrA-1imvA:
14.29
4odrB-1imvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 11 PRO A 395
LEU A 370
ILE A 254
LEU A 246
ILE A 392
 None
 0.90A 4odrA-1imvA:
undetectable
4odrB-1imvA:
undetectable		 4odrA-1imvA:
14.29
4odrB-1imvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 12 LEU A 370
TRP A 197
LEU A 248
PHE A 256
PHE A 376
 None
 1.37A 5ieoA-1imvA:
undetectable		 5ieoA-1imvA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 7 VAL A  65
PHE A  41
LEU A 309
THR A 306
 None
 0.91A 5m78A-1imvA:
0.0		 5m78A-1imvA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		5 / 7 LEU A  72
ALA A  76
THR A  80
ILE A  83
LEU A 317
 None
 1.43A 5te8A-1imvA:
0.1		 5te8A-1imvA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 8 THR A  67
TYR A 142
THR A 144
ARG A 121
 None
 1.29A 5tzoA-1imvA:
undetectable		 5tzoA-1imvA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 8 THR A  67
TYR A 142
THR A 144
ARG A 121
 None
 1.33A 5tzoB-1imvA:
undetectable		 5tzoB-1imvA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 8 THR A  67
TYR A 142
THR A 144
ARG A 121
 None
 1.33A 5tzoC-1imvA:
undetectable		 5tzoC-1imvA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 4 TYR A  46
ARG A  47
THR A 267
LEU A 266
 None
None
NAG  A 401 ( 4.9A)
None
 1.43A 5x19W-1imvA:
0.0		 5x19W-1imvA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		3 / 3 SER A  73
HIS A  99
TYR A 142
 None
 1.02A 5y2tA-1imvA:
0.0		 5y2tA-1imvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 7 SER A  61
SER A  64
GLY A 189
LEU A 116
 None
 1.14A 6btxA-1imvA:
0.0		 6btxA-1imvA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		3 / 3 TYR A 102
ALA A 385
LEU A  63
 None
 0.71A 6d9kF-1imvA:
0.0		 6d9kF-1imvA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR
(Homo
sapiens) 		4 / 6 TYR A 212
VAL A 221
VAL A 219
THR A 218
 None
 1.43A 6f32B-1imvA:
undetectable		 6f32B-1imvA:
22.71