SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ind'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1ind IGG1-LAMBDA CHA255
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 7 SER H 202
ALA H 201
SER H 203
THR H 204
 None
 1.08A 2i91A-1indH:
undetectable		 2i91A-1indH:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1ind IGG1-LAMBDA CHA255
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 7 SER H 202
ALA H 201
SER H 203
THR H 204
 None
 1.08A 2i91B-1indH:
undetectable		 2i91B-1indH:
17.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 1ind IGG1-LAMBDA CHA255
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 12 VAL H   2
ALA H  24
MET H  34
ARG H  72
ASN H  77
 None
 0.93A 3qxtA-1indH:
19.6		 3qxtA-1indH:
36.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 1ind IGG1-LAMBDA CHA255
FAB (HEAVY CHAIN)
(Mus
musculus) 		3 / 3 THR H 132
ASN H 133
SER H 134
 None
 0.76A 4tvtA-1indH:
0.0		 4tvtA-1indH:
23.89