SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1inl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 11 GLY A  98
GLY A 100
GLU A 121
GLY A 153
LEU A 182
 None
 0.87A 1jg3A-1inlA:
7.9		 1jg3A-1inlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 11 GLY A  98
GLY A 100
GLU A 121
GLY A 153
LEU A 182
 None
 0.87A 1jg3B-1inlA:
2.9		 1jg3B-1inlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 100
GLY A 103
VAL A 122
ASP A 123
VAL A 126
 None
 0.94A 1n2xA-1inlA:
14.0		 1n2xA-1inlA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 100
GLY A 102
GLY A 103
ASP A 123
VAL A 126
 None
 0.86A 1n2xB-1inlA:
13.9		 1n2xB-1inlA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_A_PAUA6001_0
(PANTOTHENATE KINASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 9 ASP A 101
GLY A  98
HIS A  77
LEU A 119
ILE A 169
 None
 1.29A 1sq5A-1inlA:
0.0		 1sq5A-1inlA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_B_PAUB6003_0
(PANTOTHENATE KINASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 10 ASP A 101
GLY A  98
HIS A  77
LEU A 119
ILE A 169
 None
 1.26A 1sq5B-1inlA:
0.0		 1sq5B-1inlA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_C_PAUC6002_0
(PANTOTHENATE KINASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 9 ASP A 101
GLY A  98
HIS A  77
LEU A 119
ILE A 169
 None
 1.28A 1sq5C-1inlA:
0.0		 1sq5C-1inlA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 10 ASP A 101
GLY A  98
HIS A  77
LEU A 119
ILE A 169
 None
 1.27A 1sq5D-1inlA:
0.0		 1sq5D-1inlA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		3 / 3 GLY A  98
GLU A 121
ASP A 170
 None
 0.62A 2b25B-1inlA:
10.5		 2b25B-1inlA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		3 / 3 VAL A 200
VAL A  83
ASP A 112
 None
 0.70A 2fumD-1inlA:
2.0		 2fumD-1inlA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 7 SER A 171
PHE A 187
ILE A 169
GLY A 153
 None
 0.93A 2y7kA-1inlA:
undetectable		 2y7kA-1inlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		3 / 3 MET A  67
GLU A 121
ASN A 152
 None
 0.63A 3a27A-1inlA:
7.1		 3a27A-1inlA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 8 LEU A  62
PHE A  60
ALA A 129
ALA A 130
 None
 0.80A 3ax9B-1inlA:
undetectable		 3ax9B-1inlA:
13.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7P_A_SPMA501_1
(SPERMIDINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		6 / 12 TYR A  76
HIS A  77
ASP A 101
ASP A 170
TYR A 239
PRO A 240
 None
 0.32A 3b7pA-1inlA:
37.6		 3b7pA-1inlA:
37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7P_B_SPMB502_1
(SPERMIDINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		6 / 12 TYR A  76
HIS A  77
ASP A 101
ASP A 170
TYR A 239
PRO A 240
 None
 0.38A 3b7pB-1inlA:
38.1		 3b7pB-1inlA:
37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		7 / 12 TYR A  76
HIS A  77
ASP A 101
ASP A 170
GLU A 206
TYR A 239
PRO A 240
 None
 0.54A 3b7pC-1inlA:
38.5		 3b7pC-1inlA:
37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		8 / 12 GLN A  46
TYR A  76
HIS A  77
ILE A  97
GLY A  98
ASP A 123
VAL A 126
GLY A 153
 None
 0.55A 3bwcA-1inlA:
36.6		 3bwcA-1inlA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		10 / 12 LEU A  62
TYR A  76
HIS A  77
ILE A  97
GLY A  98
ASP A 101
ASP A 123
VAL A 126
GLY A 153
ASP A 170
 None
 0.48A 3bwcB-1inlA:
36.4		 3bwcB-1inlA:
36.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_A_SPMA501_1
(SPERMINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 11 TYR A  76
ASP A 101
ASP A 170
TYR A 239
TRP A 244
 None
 0.69A 3c6mA-1inlA:
23.4		 3c6mA-1inlA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_B_SPMB501_1
(SPERMINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 9 TYR A  76
ASP A 101
ASP A 170
TYR A 239
TRP A 244
 None
 0.71A 3c6mB-1inlA:
23.3		 3c6mB-1inlA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_C_SPMC501_1
(SPERMINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 10 TYR A  76
ASP A 101
ASP A 170
TYR A 239
TRP A 244
 None
 0.70A 3c6mC-1inlA:
23.4		 3c6mC-1inlA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_D_SPMD501_1
(SPERMINE SYNTHASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 10 TYR A  76
ASP A 101
ASP A 170
TYR A 239
TRP A 244
 None
 0.70A 3c6mD-1inlA:
23.4		 3c6mD-1inlA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 7 GLY A  98
GLY A 100
THR A 104
GLU A 121
 None
 0.74A 3fpjB-1inlA:
9.7		 3fpjB-1inlA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 103
LEU A  80
LEU A 109
SER A 138
GLY A  98
 None
 0.93A 3g2oA-1inlA:
13.0		 3g2oA-1inlA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		6 / 12 GLY A 102
GLY A 103
VAL A 122
ASP A 123
ASP A 170
LEU A 182
 None
 0.78A 3m6vA-1inlA:
10.5		 3m6vA-1inlA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		6 / 12 GLY A 102
GLY A 103
VAL A 122
ASP A 123
ASP A 170
LEU A 182
 None
 0.78A 3m6vB-1inlA:
10.4		 3m6vB-1inlA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 102
GLY A 103
VAL A 122
ASP A 123
LEU A 182
 None
 0.62A 3m6wA-1inlA:
10.4		 3m6wA-1inlA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		3 / 3 GLY A 100
GLY A 102
THR A 104
 None
 0.42A 3si7B-1inlA:
undetectable		 3si7B-1inlA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 8 TYR A 188
CYH A 191
ILE A 168
ILE A  97
 None
 0.97A 4afgD-1inlA:
0.0
4afgE-1inlA:
0.0		 4afgD-1inlA:
21.05
4afgE-1inlA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 102
GLY A 103
GLY A 153
ASP A 170
LEU A 182
 None
 0.87A 4fp9A-1inlA:
10.7		 4fp9A-1inlA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 102
GLY A 103
GLY A 153
ASP A 170
LEU A 182
 None
 0.87A 4fp9C-1inlA:
10.6		 4fp9C-1inlA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 GLY A 102
GLY A 103
GLY A 153
ASP A 170
LEU A 182
 None
 0.86A 4fp9F-1inlA:
10.8		 4fp9F-1inlA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 5 TYR A 239
LEU A  30
GLU A  21
TYR A  23
 None
 1.33A 4olaA-1inlA:
undetectable		 4olaA-1inlA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 ASP A  63
VAL A 126
LEU A 125
ILE A  48
GLY A  41
 None
 1.10A 4y8wA-1inlA:
undetectable		 4y8wA-1inlA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 5 TYR A 239
LEU A  30
GLU A  21
TYR A  23
 None
 1.26A 5js1A-1inlA:
2.3		 5js1A-1inlA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		5 / 12 PHE A 141
ALA A 130
LEU A 134
PHE A  60
LEU A 109
 None
 1.11A 5ljcA-1inlA:
undetectable		 5ljcA-1inlA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 7 GLY A 100
GLY A 102
GLU A 121
ASN A 152
 None
 0.74A 5ybbB-1inlA:
8.1		 5ybbB-1inlA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1inl SPERMIDINE SYNTHASE
(Thermotoga
maritima) 		4 / 7 TYR A  76
VAL A 264
GLY A  99
ALA A  81
 None
 0.89A 6hd6B-1inlA:
undetectable		 6hd6B-1inlA:
14.19