SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1inp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 11 ILE A 201
LEU A 302
PRO A 235
VAL A 264
ASP A 304
 None
 1.38A 1mrlA-1inpA:
0.0
1mrlB-1inpA:
undetectable		 1mrlA-1inpA:
18.70
1mrlB-1inpA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 12 ILE A 201
LEU A 302
PRO A 235
VAL A 264
ASP A 304
 None
 1.42A 1mrlB-1inpA:
0.0
1mrlC-1inpA:
0.0		 1mrlB-1inpA:
18.70
1mrlC-1inpA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 10 VAL A 237
LEU A 300
TYR A 220
LEU A 296
TYR A 293
 None
 1.30A 1pbcA-1inpA:
undetectable		 1pbcA-1inpA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 12 TYR A 220
LEU A 296
LEU A 302
THR A 239
ILE A 230
 None
 1.28A 1tw4B-1inpA:
0.1		 1tw4B-1inpA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		3 / 3 SER A 318
ASP A 334
CYH A 338
 None
 1.13A 2br4E-1inpA:
undetectable		 2br4E-1inpA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 6 ALA A  53
TYR A 161
ILE A  18
ILE A 155
 None
 1.15A 2dcfA-1inpA:
0.0		 2dcfA-1inpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		3 / 3 ILE A 307
ILE A 285
LEU A 325
 None
 0.57A 2prgA-1inpA:
undetectable		 2prgA-1inpA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 8 PRO A 253
PRO A 235
VAL A 237
SER A 238
 None
 1.00A 2v41C-1inpA:
undetectable
2v41D-1inpA:
undetectable		 2v41C-1inpA:
19.76
2v41D-1inpA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 10 TYR A 220
ILE A 201
TYR A 293
LEU A 300
LEU A 233
 None
 1.44A 2w98A-1inpA:
undetectable		 2w98A-1inpA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 7 ALA A  53
TYR A 161
ILE A  18
ILE A 155
 None
 1.12A 2zm7A-1inpA:
0.0		 2zm7A-1inpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		3 / 3 GLY A 292
ASP A 156
SER A 157
 None
MG  A 401 ( 4.3A)
None
 0.56A 3brfA-1inpA:
undetectable		 3brfA-1inpA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 8 LEU A  96
LEU A  56
ILE A  92
VAL A 110
LEU A 107
 None
 1.25A 3kp6A-1inpA:
undetectable
3kp6B-1inpA:
undetectable		 3kp6A-1inpA:
19.28
3kp6B-1inpA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 9 GLY A 227
ILE A 143
MET A 198
GLY A 222
ILE A 230
 None
 1.00A 3ogpA-1inpA:
undetectable		 3ogpA-1inpA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 9 GLY A 227
ILE A 143
MET A 198
GLY A 222
ILE A 230
 None
 1.00A 3ogpB-1inpA:
undetectable		 3ogpB-1inpA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		5 / 10 TYR A 306
ILE A 305
SER A 309
ILE A 265
ALA A 303
 None
 1.35A 3u6tA-1inpA:
undetectable		 3u6tA-1inpA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		3 / 3 ASN A  82
GLU A  59
ARG A  95
 None
 0.70A 3wxoA-1inpA:
0.0		 3wxoA-1inpA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 5 VAL A 188
LEU A 148
ILE A   4
LEU A   5
 None
 0.86A 4mghA-1inpA:
0.0		 4mghA-1inpA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 7 GLU A  38
GLU A  40
GLU A  79
GLU A  80
 None
None
MG  A 402 ( 3.1A)
None
 1.13A 4mi4B-1inpA:
0.2
4mi4C-1inpA:
0.0		 4mi4B-1inpA:
19.59
4mi4C-1inpA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 8 GLU A  38
GLU A  40
GLU A  79
GLU A  80
 None
None
MG  A 402 ( 3.1A)
None
 1.14A 4mj8A-1inpA:
0.2
4mj8C-1inpA:
0.1		 4mj8A-1inpA:
19.06
4mj8C-1inpA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		3 / 3 LEU A  56
LEU A  96
ARG A  10
 None
 0.63A 5hnzB-1inpA:
undetectable		 5hnzB-1inpA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 5 SER A 118
ALA A 117
GLN A  25
THR A  27
 None
 1.26A 5n4iA-1inpA:
undetectable		 5n4iA-1inpA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 8 ILE A 374
LEU A 335
ILE A 307
ILE A 265
 None
 0.70A 5numA-1inpA:
undetectable		 5numA-1inpA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 8 ARG A 377
ALA A 303
VAL A 264
SER A 262
 None
 0.85A 5v0vA-1inpA:
0.4		 5v0vA-1inpA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 6 GLY A 292
THR A 183
GLN A 203
TYR A 220
 None
 1.15A 6ag0A-1inpA:
undetectable		 6ag0A-1inpA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE
(Bos
taurus) 		4 / 6 GLY A 292
THR A 183
GLN A 203
TYR A 220
 None
 1.16A 6ag0C-1inpA:
undetectable		 6ag0C-1inpA:
12.08