SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ipi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		3 / 3 PHE A  21
LEU A 113
LEU A 109
 None
 0.61A 1mx1E-1ipiA:
undetectable		 1mx1E-1ipiA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		3 / 3 ARG A  60
GLU A  97
TYR A  56
 None
 0.95A 3k37B-1ipiA:
0.0		 3k37B-1ipiA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 10 LEU A  12
ALA A  36
GLY A  74
ILE A  75
VAL A  47
 None
 0.93A 3ogpA-1ipiA:
0.0		 3ogpA-1ipiA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 12 GLU A   9
LEU A 109
LEU A  16
LEU A  43
ALA A  79
 None
 1.08A 5v0vA-1ipiA:
undetectable		 5v0vA-1ipiA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 9 VAL A  77
VAL A 107
LEU A  43
GLY A 114
LEU A 113
 None
 1.31A 6czmA-1ipiA:
0.0
6czmB-1ipiA:
0.0		 6czmA-1ipiA:
16.29
6czmB-1ipiA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 9 VAL A  77
VAL A 107
LEU A  43
GLY A 114
LEU A 113
 None
 1.31A 6czmB-1ipiA:
0.0
6czmC-1ipiA:
undetectable		 6czmB-1ipiA:
16.29
6czmC-1ipiA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 8 GLY A 114
LEU A 113
VAL A  77
VAL A 107
LEU A  43
 None
 1.29A 6czmD-1ipiA:
undetectable
6czmF-1ipiA:
undetectable		 6czmD-1ipiA:
16.29
6czmF-1ipiA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 9 VAL A  77
VAL A 107
LEU A  43
GLY A 114
LEU A 113
 None
 1.30A 6czmD-1ipiA:
0.0
6czmE-1ipiA:
0.0		 6czmD-1ipiA:
16.29
6czmE-1ipiA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1ipi HOLLIDAY JUNCTION
RESOLVASE
(Pyrococcus
furiosus) 		5 / 10 VAL A  77
VAL A 107
LEU A  43
GLY A 114
LEU A 113
 None
 1.29A 6czmE-1ipiA:
0.0
6czmF-1ipiA:
0.0		 6czmE-1ipiA:
16.29
6czmF-1ipiA:
16.29