SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ipk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		4 / 6 LEU A 125
LEU A 244
LEU A 111
LEU A  62
 None
 0.93A 1errA-1ipkA:
undetectable		 1errA-1ipkA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 7 LEU A  33
GLY A 339
ILE A 271
VAL A 316
ILE A  51
 None
 1.34A 2aojB-1ipkA:
undetectable		 2aojB-1ipkA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		4 / 6 LEU A 125
ASN A  37
ILE A 340
PHE A 338
 None
 0.99A 2jn3A-1ipkA:
0.3		 2jn3A-1ipkA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		3 / 3 PHE A  11
ASN A   9
PHE A 317
 None
 1.04A 2zbuD-1ipkA:
undetectable		 2zbuD-1ipkA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 10 ILE A 319
PHE A 325
ILE A 283
LEU A 262
HIS A 265
 None
 1.14A 3o1cA-1ipkA:
undetectable		 3o1cA-1ipkA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 10 ILE A 319
PHE A 325
ILE A 283
LEU A 262
HIS A 265
 None
 1.11A 3o1xA-1ipkA:
undetectable		 3o1xA-1ipkA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 10 ILE A 319
PHE A 325
ILE A 283
SER A 252
LEU A 262
 None
 1.01A 3o1xA-1ipkA:
undetectable		 3o1xA-1ipkA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 10 ILE A 319
PHE A 325
ILE A 283
LEU A 262
HIS A 265
 None
 1.12A 3qgzA-1ipkA:
undetectable		 3qgzA-1ipkA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 10 ILE A 319
PHE A 325
ILE A 283
SER A 252
LEU A 262
 None
 1.01A 3qgzA-1ipkA:
undetectable		 3qgzA-1ipkA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		3 / 3 ASN A 345
ALA A 342
LYS A 269
 None
 0.93A 3runA-1ipkA:
0.0		 3runA-1ipkA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		3 / 3 PHE A  11
SER A  40
GLN A  42
 None
 0.99A 3smtA-1ipkA:
0.0		 3smtA-1ipkA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		3 / 3 PHE A 138
VAL A  52
ILE A  30
 None
 0.56A 4emaA-1ipkA:
undetectable		 4emaA-1ipkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 12 LEU A 262
ALA A 329
GLY A 279
VAL A 254
ILE A 256
 None
 0.96A 4hlaA-1ipkA:
undetectable		 4hlaA-1ipkA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 9 VAL A  52
ILE A  51
ARG A  50
ILE A 123
GLY A 339
 None
 1.04A 4kukA-1ipkA:
undetectable		 4kukA-1ipkA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		4 / 5 VAL A 327
LEU A 274
VAL A 272
PHE A 325
 None
 0.98A 4lb0B-1ipkA:
undetectable		 4lb0B-1ipkA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZP0_A_DXCA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		5 / 10 ASN A 334
ASP A 255
LEU A 336
LEU A 219
GLY A 339
 None
 1.16A 4zp0A-1ipkA:
undetectable		 4zp0A-1ipkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		4 / 6 ILE A 195
ILE A 122
LEU A  95
PHE A  71
 None
 0.99A 5vkqB-1ipkA:
undetectable
5vkqC-1ipkA:
undetectable		 5vkqB-1ipkA:
13.26
5vkqC-1ipkA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		4 / 6 ILE A 195
ILE A 122
LEU A  95
PHE A  71
 None
 0.97A 5vkqC-1ipkA:
undetectable
5vkqD-1ipkA:
undetectable		 5vkqC-1ipkA:
13.26
5vkqD-1ipkA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		4 / 7 LEU A 244
PHE A 217
LEU A 251
PHE A 338
 None
 0.95A 5z84C-1ipkA:
undetectable
5z84J-1ipkA:
0.0		 5z84C-1ipkA:
18.72
5z84J-1ipkA:
7.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CB4_A_BEZA501_0
(CANAVALIN)		 1ipk BETA-CONGLYCININ,
BETA CHAIN
(Glycine
max) 		6 / 8 HIS A 265
ASN A 267
VAL A 272
LEU A 274
ILE A 319
ARG A 347
 None
 0.65A 6cb4A-1ipkA:
47.0		 6cb4A-1ipkA:
54.30