SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLY A  37
PHE A  67
VAL A  68
LEU A  64
ALA A   9
 None
 1.31A 1e3vA-1iq0A:
0.0		 1e3vA-1iq0A:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 LEU A 510
GLU A 513
THR A 576
LEU A 507
 None
 1.23A 1etb2-1iq0A:
undetectable		 1etb2-1iq0A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 136
ALA A 139
VAL A 352
 None
 1.34A 1fm6A-1iq0A:
undetectable		 1fm6A-1iq0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
 None
 1.38A 1fm9A-1iq0A:
undetectable		 1fm9A-1iq0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
 None
 1.35A 1k74A-1iq0A:
undetectable		 1k74A-1iq0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 11 ARG A   3
ARG A   4
LEU A 517
GLU A 521
ALA A 520
 None
 1.28A 1mjlA-1iq0A:
undetectable
1mjlB-1iq0A:
undetectable		 1mjlA-1iq0A:
10.92
1mjlB-1iq0A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 11 HIS A 526
ARG A   4
LEU A 517
GLU A 521
ALA A 519
 None
 1.16A 1mjlA-1iq0A:
undetectable
1mjlB-1iq0A:
undetectable		 1mjlA-1iq0A:
10.92
1mjlB-1iq0A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 MET A 446
GLY A 470
GLN A 474
LEU A 439
ILE A 455
 None
 1.05A 1p93B-1iq0A:
undetectable		 1p93B-1iq0A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 HIS A 119
GLY A 121
HIS A 122
GLN A 357
VAL A 388
 None
 0.89A 1qu2A-1iq0A:
undetectable		 1qu2A-1iq0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 HIS A 228
TYR A 329
TYR A 234
LEU A 332
 None
 1.13A 1qzrA-1iq0A:
0.9		 1qzrA-1iq0A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 HIS A 228
TYR A 329
TYR A 234
LEU A 332
 None
 1.13A 1qzrB-1iq0A:
0.8		 1qzrB-1iq0A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		7 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
VAL A 352
 None
 1.48A 1xlsA-1iq0A:
undetectable		 1xlsA-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
LEU A 583
LEU A 136
ALA A 139
VAL A 352
 None
 1.46A 1xlsA-1iq0A:
undetectable		 1xlsA-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		7 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
VAL A 352
 None
 1.48A 1xlsB-1iq0A:
undetectable		 1xlsB-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
LEU A 583
LEU A 136
ALA A 139
VAL A 352
 None
 1.46A 1xlsB-1iq0A:
undetectable		 1xlsB-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		7 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
VAL A 352
 None
 1.48A 1xlsC-1iq0A:
undetectable		 1xlsC-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
LEU A 583
LEU A 136
ALA A 139
VAL A 352
 None
 1.46A 1xlsC-1iq0A:
undetectable		 1xlsC-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		7 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
VAL A 352
 None
 1.47A 1xlsD-1iq0A:
undetectable		 1xlsD-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
LEU A 583
LEU A 136
ALA A 139
VAL A 352
 None
 1.46A 1xlsD-1iq0A:
undetectable		 1xlsD-1iq0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 ILE A 132
ALA A 520
ALA A 519
LEU A 528
LEU A 136
ALA A 139
 None
 1.33A 2aclG-1iq0A:
undetectable		 2aclG-1iq0A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 VAL A 143
VAL A 145
GLU A 348
ILE A 132
ALA A 519
 None
 0.93A 2gj5A-1iq0A:
undetectable		 2gj5A-1iq0A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 10 LEU A  88
ALA A  91
GLU A  90
LEU A 510
LEU A 505
 None
 1.44A 2ocfA-1iq0A:
0.4		 2ocfA-1iq0A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 PRO A 587
ASN A 231
ARG A 134
 None
 0.96A 2qeuB-1iq0A:
0.3		 2qeuB-1iq0A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 HIS A 427
PHE A 465
GLN A 474
PRO A 471
 None
 1.33A 2qqtA-1iq0A:
0.0		 2qqtA-1iq0A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLU A 513
ASP A 511
TYR A  36
 None
 0.73A 2yvlB-1iq0A:
undetectable		 2yvlB-1iq0A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ILE A 149
LEU A 237
MET A 227
THR A 226
 None
 1.02A 3ag2N-1iq0A:
0.2
3ag2W-1iq0A:
0.0		 3ag2N-1iq0A:
22.20
3ag2W-1iq0A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ILE A 149
LEU A 237
MET A 227
THR A 226
 None
 1.03A 3ag4N-1iq0A:
0.4
3ag4W-1iq0A:
0.0		 3ag4N-1iq0A:
22.20
3ag4W-1iq0A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 5 VAL A 104
VAL A 105
THR A 343
ARG A 141
 None
 1.24A 3bjwD-1iq0A:
0.0		 3bjwD-1iq0A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 VAL A 420
LYS A 423
HIS A 477
 None
 0.72A 3elzA-1iq0A:
0.0		 3elzA-1iq0A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 TYR A 184
GLY A 153
THR A 159
GLU A 240
 None
 0.96A 3fpjA-1iq0A:
undetectable		 3fpjA-1iq0A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ASN A 351
PRO A 525
ALA A 519
ALA A 520
LEU A 136
 None
 0.98A 3mteB-1iq0A:
undetectable		 3mteB-1iq0A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ASN A 351
PRO A 525
ALA A 519
ALA A 520
LEU A 136
 None
 1.00A 3p2kA-1iq0A:
undetectable		 3p2kA-1iq0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 ALA A 222
PHE A 179
ALA A 180
THR A 159
 None
 0.97A 3t3sE-1iq0A:
0.0		 3t3sE-1iq0A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLY A 153
ASP A 150
SER A 241
GLU A 158
ALA A 156
 None
 1.25A 3t7sA-1iq0A:
undetectable		 3t7sA-1iq0A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLY A 153
ASP A 150
SER A 241
GLU A 158
ALA A 156
 None
 1.24A 3t7sB-1iq0A:
undetectable		 3t7sB-1iq0A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLY A 153
ASP A 150
SER A 241
GLU A 158
ALA A 156
 None
 1.24A 3t7sD-1iq0A:
undetectable		 3t7sD-1iq0A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 LEU A  78
VAL A  68
LEU A  64
ALA A   9
 None
 0.93A 3uniB-1iq0A:
0.0		 3uniB-1iq0A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ILE A 149
LEU A 237
MET A 227
THR A 226
 None
 0.99A 3wg7A-1iq0A:
2.1
3wg7J-1iq0A:
0.0		 3wg7A-1iq0A:
22.20
3wg7J-1iq0A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 8 GLY A 247
ALA A 246
ASP A 242
PRO A 344
THR A 343
 None
 1.38A 4eyrB-1iq0A:
undetectable		 4eyrB-1iq0A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 5 HIS A 481
ALA A 588
HIS A 477
GLN A 574
 None
 1.42A 4gboA-1iq0A:
undetectable		 4gboA-1iq0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A  43
LEU A  47
ILE A  54
GLY A  18
LEU A  14
 None
 1.04A 4lmnA-1iq0A:
undetectable		 4lmnA-1iq0A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 MET A 446
GLY A 470
GLN A 474
LEU A 439
ILE A 455
 None
 1.04A 4p6xA-1iq0A:
undetectable		 4p6xA-1iq0A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 PRO A 471
ILE A 126
SER A 464
 None
 0.71A 5fsaA-1iq0A:
0.0		 5fsaA-1iq0A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 5 HIS A 481
ALA A 588
HIS A 477
GLN A 574
 None
 1.39A 5uizA-1iq0A:
undetectable		 5uizA-1iq0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 LEU A 220
LEU A 221
GLY A 331
TYR A 328
 None
 0.89A 6ce2A-1iq0A:
undetectable		 6ce2A-1iq0A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 4 ILE A 132
LEU A 584
HIS A 526
ALA A 529
 None
 0.98A 6ck2C-1iq0A:
undetectable
6ck2D-1iq0A:
undetectable		 6ck2C-1iq0A:
2.85
6ck2D-1iq0A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 5 LEU A 160
THR A 152
PRO A 337
ARG A 322
 None
 0.95A 6ew0F-1iq0A:
0.0		 6ew0F-1iq0A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 LEU A 160
THR A 152
PRO A 337
ARG A 322
 None
 0.95A 6ew0G-1iq0A:
0.3		 6ew0G-1iq0A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1iq0 ARGINYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ILE A 149
LEU A 237
MET A 227
THR A 226
 None
 0.90A 6nmfN-1iq0A:
0.0
6nmfW-1iq0A:
0.0		 6nmfN-1iq0A:
22.20
6nmfW-1iq0A:
8.17