SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 1iq4 50S RIBOSOMAL
PROTEIN L5
(Geobacillus
stearothermophil
us) 		3 / 3 TYR A 128
VAL A 117
THR A 129
 None
 0.58A 2ygnA-1iq4A:
undetectable		 2ygnA-1iq4A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1iq4 50S RIBOSOMAL
PROTEIN L5
(Geobacillus
stearothermophil
us) 		5 / 10 TYR A 128
LEU A 130
LEU A 103
ILE A 104
LEU A 100
 None
 0.95A 4odoC-1iq4A:
undetectable		 4odoC-1iq4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1iq4 50S RIBOSOMAL
PROTEIN L5
(Geobacillus
stearothermophil
us) 		4 / 5 LEU A 169
THR A 158
THR A 162
GLY A 126
 None
 1.28A 6gtqA-1iq4A:
1.2		 6gtqA-1iq4A:
23.15