SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		4 / 6 VAL A  99
THR A 100
GLU A 127
LEU A 111
 None
 1.14A 1s8fB-1iq6A:
undetectable		 1s8fB-1iq6A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 THR A  94
SER A  14
ARG A  12
 None
 0.83A 3phnA-1iq6A:
0.0		 3phnA-1iq6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		5 / 11 LEU A  77
ALA A 109
LEU A 132
GLY A  66
LEU A  65
 None
 1.26A 3uudA-1iq6A:
undetectable		 3uudA-1iq6A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		4 / 7 ALA A  95
LEU A  64
LEU A  65
ILE A 115
 None
 0.84A 4ubsA-1iq6A:
undetectable		 4ubsA-1iq6A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 ARG A  12
LYS A  10
GLU A  96
 None
 0.68A 5d0yA-1iq6A:
undetectable		 5d0yA-1iq6A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A 124
HIS A  53
VAL A  52
 None
 0.71A 5jmnC-1iq6A:
0.0		 5jmnC-1iq6A:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.58A 5qglA-1iq6A:
undetectable		 5qglA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.64A 5qgnA-1iq6A:
0.0		 5qgnA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.68A 5qguA-1iq6A:
undetectable		 5qguA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.68A 5qgvA-1iq6A:
undetectable		 5qgvA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.71A 5qgwA-1iq6A:
undetectable		 5qgwA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.68A 5qgxA-1iq6A:
undetectable		 5qgxA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.67A 5qgyA-1iq6A:
0.0		 5qgyA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.67A 5qh1A-1iq6A:
undetectable		 5qh1A-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.67A 5qh4A-1iq6A:
undetectable		 5qh4A-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.67A 5qh5A-1iq6A:
0.0		 5qh5A-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.65A 5qhcA-1iq6A:
undetectable		 5qhcA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.67A 5qheA-1iq6A:
undetectable		 5qheA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.71A 5qhfA-1iq6A:
undetectable		 5qhfA-1iq6A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1iq6 (R)-SPECIFIC
ENOYL-COA HYDRATASE
(Aeromonas
caviae) 		3 / 3 VAL A  52
VAL A  87
GLN A 118
 None
 0.64A 5qhgA-1iq6A:
undetectable		 5qhgA-1iq6A:
23.23