SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 ALA A 462
VAL A 465
TRP A 464
 None
 0.95A 1c4dA-1iq7A:
undetectable
1c4dB-1iq7A:
undetectable		 1c4dA-1iq7A:
3.41
1c4dB-1iq7A:
3.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 ILE A 665
LEU A 657
GLU A 588
ALA A 587
VAL A 664
 None
 1.32A 1ctrA-1iq7A:
undetectable		 1ctrA-1iq7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 ILE A 665
ASN A 473
ASP A 659
GLY A 658
PHE A 661
 None
NAG  A 705 (-2.8A)
None
None
None
 1.27A 1hvyB-1iq7A:
0.0		 1hvyB-1iq7A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 GLU A 684
ILE A 665
TYR A 662
GLY A 658
 None
 1.13A 1maaB-1iq7A:
undetectable
1maaD-1iq7A:
undetectable		 1maaB-1iq7A:
20.58
1maaD-1iq7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		4 / 8 SER A 517
SER A 516
GLY A 491
GLY A 504
 None
 0.77A 1me7A-1iq7A:
undetectable		 1me7A-1iq7A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		3 / 3 PHE A 628
LEU A 644
LEU A 608
 None
 0.67A 1mx1E-1iq7A:
undetectable		 1mx1E-1iq7A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 11 ARG A 344
LEU A 607
ALA A 391
GLY A 387
ILE A 604
 None
 0.94A 1t3rB-1iq7A:
undetectable		 1t3rB-1iq7A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 11 LEU A 528
LEU A 531
LEU A 569
VAL A 443
VAL A 578
 None
 1.37A 2po5B-1iq7A:
undetectable		 2po5B-1iq7A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 10 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.24A 2wscB-1iq7A:
undetectable		 2wscB-1iq7A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 10 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.23A 2wseB-1iq7A:
undetectable		 2wseB-1iq7A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.23A 2wsfB-1iq7A:
undetectable		 2wsfB-1iq7A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 ARG A 344
LEU A 607
ALA A 391
GLY A 387
ILE A 604
 None
 0.95A 3em6B-1iq7A:
undetectable		 3em6B-1iq7A:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 10 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.23A 3lw5B-1iq7A:
undetectable		 3lw5B-1iq7A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 11 ARG A 344
LEU A 607
ALA A 391
GLY A 387
ILE A 604
 None
 0.95A 3oy4A-1iq7A:
undetectable		 3oy4A-1iq7A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_B_CP6B609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 10 ILE A 665
ASP A 395
SER A 674
ILE A 676
THR A 461
 None
SO4  A 701 (-4.9A)
None
None
SO4  A 701 (-3.2A)
 1.17A 3qgtB-1iq7A:
undetectable		 3qgtB-1iq7A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 LEU A 569
LEU A 448
PHE A 539
ALA A 433
SER A 441
 None
 1.22A 4aqlA-1iq7A:
undetectable		 4aqlA-1iq7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 ARG A 344
LEU A 607
ALA A 391
GLY A 387
ILE A 604
 None
 0.94A 4dqbA-1iq7A:
undetectable		 4dqbA-1iq7A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 11 ARG A 344
LEU A 607
ALA A 391
GLY A 387
ILE A 604
 None
 0.96A 4dqhA-1iq7A:
undetectable		 4dqhA-1iq7A:
14.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 GLY A 469
VAL A 664
GLY A 397
TYR A 400
 None
 0.58A 4dxuA-1iq7A:
36.6		 4dxuA-1iq7A:
51.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 12 ARG A 575
GLY A 573
ARG A 474
VAL A 545
VAL A 578
 None
 1.35A 4ffwA-1iq7A:
undetectable		 4ffwA-1iq7A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		4 / 7 MET A 468
ARG A 460
TRP A 464
ALA A 457
 None
 1.08A 4xk8A-1iq7A:
0.0		 4xk8A-1iq7A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.19A 4y28B-1iq7A:
undetectable		 4y28B-1iq7A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 10 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.24A 5oy0b-1iq7A:
undetectable		 5oy0b-1iq7A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 ASP A 481
ALA A 457
PHE A 484
GLY A 487
GLY A 491
 None
 1.27A 6awoA-1iq7A:
undetectable		 6awoA-1iq7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 ASP A 481
ALA A 457
PHE A 484
GLY A 487
GLY A 491
 None
 1.28A 6awqA-1iq7A:
0.0		 6awqA-1iq7A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		4 / 6 MET A 468
ARG A 460
TRP A 464
ALA A 457
 None
 1.18A 6fosB-1iq7A:
undetectable		 6fosB-1iq7A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1iq7 OVOTRANSFERRIN
(Gallus
gallus) 		5 / 9 MET A 468
ARG A 460
TRP A 464
ALA A 457
ALA A 462
 None
 1.17A 6hqbB-1iq7A:
undetectable		 6hqbB-1iq7A:
14.68