SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iqc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 VAL A 113
ALA A 110
HIS A 107
 None
 0.74A 1q23C-1iqcA:
0.0		 1q23C-1iqcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 VAL A 113
ALA A 110
HIS A 107
 None
 0.76A 1q23H-1iqcA:
0.0		 1q23H-1iqcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 VAL A 113
ALA A 110
HIS A 107
 None
 0.74A 1q23L-1iqcA:
undetectable		 1q23L-1iqcA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 ASP A 157
LEU A 160
HIS A 187
 None
None
HEM  A 402 (-3.3A)
 0.74A 1qknA-1iqcA:
0.0		 1qknA-1iqcA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		4 / 6 ARG A 215
GLY A  84
ALA A  86
LEU A  78
 None
 1.00A 3bgdA-1iqcA:
undetectable		 3bgdA-1iqcA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 ASN A 268
ASP A 170
GLN A 169
 None
 0.81A 3eeyD-1iqcA:
undetectable		 3eeyD-1iqcA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		5 / 6 ALA A 110
ILE A 138
LEU A  31
GLU A 108
ALA A  98
 None
 1.38A 3r9sA-1iqcA:
undetectable		 3r9sA-1iqcA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		5 / 12 ASN A  77
LEU A 282
ARG A 234
ILE A   8
THR A 151
 HEM  A 401 (-3.5A)
None
None
None
None
 1.28A 4o5fA-1iqcA:
undetectable
4o5fB-1iqcA:
undetectable		 4o5fA-1iqcA:
22.26
4o5fB-1iqcA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		4 / 5 SER A 181
ARG A 265
GLU A 271
PHE A 267
 None
None
None
HEM  A 402 (-4.7A)
 0.84A 4r82A-1iqcA:
0.0
4r82B-1iqcA:
0.0		 4r82A-1iqcA:
19.61
4r82B-1iqcA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		4 / 5 SER A 181
GLY A 180
ARG A 265
PHE A 267
 None
None
None
HEM  A 402 (-4.7A)
 1.06A 4r82A-1iqcA:
0.0
4r82B-1iqcA:
0.0		 4r82A-1iqcA:
19.61
4r82B-1iqcA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		5 / 12 ILE A 142
GLY A  22
VAL A 127
ALA A 143
ALA A  93
 HEM  A 401 (-4.4A)
None
None
None
HEM  A 401 ( 4.6A)
 1.12A 5n0oB-1iqcA:
undetectable		 5n0oB-1iqcA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 ARG A  30
PHE A  26
LEU A 294
 None
HEM  A 401 ( 4.9A)
None
 0.77A 5x1bC-1iqcA:
undetectable		 5x1bC-1iqcA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		5 / 12 TYR A 242
TYR A 206
LEU A 233
ALA A 254
LEU A 251
 None
None
HEM  A 402 (-4.8A)
HEM  A 402 ( 4.0A)
None
 1.35A 5zwrB-1iqcA:
0.0		 5zwrB-1iqcA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 1iqc DI-HEME PEROXIDASE
(Nitrosomonas
europaea) 		3 / 3 PHE A 267
ASP A 270
LYS A 274
 HEM  A 402 (-4.7A)
None
None
 0.86A 6awtD-1iqcA:
0.0		 6awtD-1iqcA:
18.84