SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FDT_A_ESTA350_1 (17-BETA-HYDROXYSTERO ID-DEHYDROGENASE)	1iqd	HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN (Homo sapiens)	5 / 11	VAL B 110 LEU B 83 SER B 67 PHE B 64 GLU B 82	None	1.19A	1fdtA-1iqdB: undetectable	1fdtA-1iqdB: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VMY_A_FFOA505_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	1iqd	HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN (Homo sapiens)	4 / 6	GLU B 149 TYR B 177 TYR B 146 PRO B 41	None	1.42A	2vmyA-1iqdB: undetectable	2vmyA-1iqdB: 19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_F_ADNF251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1iqd	HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN (Homo sapiens)	5 / 10	SER B 67 VAL B 18 GLU B 82 MET B 81 ASP B 87	None	1.32A	3u40A-1iqdB: undetectable 3u40F-1iqdB: undetectable	3u40A-1iqdB: 22.99 3u40F-1iqdB: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YMG_A_SAMA1001_1 (PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE)	1iqd	HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN (Homo sapiens)	4 / 4	SER B 83 SER B 67 GLU B 63 ASP B 87	None	1.40A	4ymgA-1iqdB: undetectable	4ymgA-1iqdB: 21.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FDT_A_ESTA350_1","17-BETA-HYDROXYSTEROID-DEHYDROGENASE","1iqd","HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN","Homo sapiens",5,"VAL B 110;LEU B  83;SER B  67;PHE B  64;GLU B  82","None","1.19A","1fdtA-1iqdB:undetectable","1fdtA-1iqdB:21.38"],["2VMY_A_FFOA505_0","SERINE HYDROXYMETHYLTRANSFERASE","1iqd","HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN","Homo sapiens",4,"GLU B 149;TYR B 177;TYR B 146;PRO B  41","None","1.42A","2vmyA-1iqdB:undetectable","2vmyA-1iqdB:19.60"],["3U40_F_ADNF251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1iqd","HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN","Homo sapiens",5,"SER B  67;VAL B  18;GLU B  82;MET B  81;ASP B  87","None","1.32A","3u40A-1iqdB:undetectable;3u40F-1iqdB:undetectable","3u40A-1iqdB:22.99;3u40F-1iqdB:22.99"],["4YMG_A_SAMA1001_1","PUTATIVE SAM-DEPENDENT O-METHYLTRANFERASE","1iqd","HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN","Homo sapiens",4,"SER B  83;SER B  67;GLU B  63;ASP B  87","None","1.40A","4ymgA-1iqdB:undetectable","4ymgA-1iqdB:21.97"]]