SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1iqq S3-RNASE
(Pyrus
pyrifolia) 		3 / 3 LEU A 164
GLU A 139
ILE A 142
 None
 0.49A 3czhA-1iqqA:
0.0		 3czhA-1iqqA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1iqq S3-RNASE
(Pyrus
pyrifolia) 		4 / 8 GLN A   9
ASN A  70
TRP A  68
GLN A  11
 None
 1.33A 4d1yA-1iqqA:
undetectable
4d1yB-1iqqA:
undetectable		 4d1yA-1iqqA:
19.38
4d1yB-1iqqA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1iqq S3-RNASE
(Pyrus
pyrifolia) 		4 / 8 GLN A  11
GLN A   9
ASN A  70
TRP A  68
 None
 1.31A 4d1yA-1iqqA:
undetectable
4d1yB-1iqqA:
undetectable		 4d1yA-1iqqA:
19.38
4d1yB-1iqqA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1iqq S3-RNASE
(Pyrus
pyrifolia) 		4 / 7 ASP A  27
GLN A  11
THR A  31
ILE A  67
 None
 1.07A 4pcuA-1iqqA:
undetectable		 4pcuA-1iqqA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 1iqq S3-RNASE
(Pyrus
pyrifolia) 		4 / 7 ILE A  96
LEU A  35
TYR A   1
GLY A 175
 None
 0.99A 4z69A-1iqqA:
undetectable		 4z69A-1iqqA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1iqq S3-RNASE
(Pyrus
pyrifolia) 		3 / 3 PRO A  37
ILE A 167
SER A  90
 None
 0.76A 5fsaA-1iqqA:
0.0		 5fsaA-1iqqA:
17.37