SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 1iqt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN D0
(Homo
sapiens) 		5 / 11 GLY A 248
LEU A 249
ASN A 246
HIS A 245
PHE A 202
 None
 1.14A 2h21B-1iqtA:
undetectable		 2h21B-1iqtA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 1iqt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN D0
(Homo
sapiens) 		5 / 11 GLY A 248
LEU A 249
ASN A 246
HIS A 245
PHE A 202
 None
 1.17A 2h21C-1iqtA:
undetectable		 2h21C-1iqtA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 1iqt HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN D0
(Homo
sapiens) 		4 / 7 PHE A 202
GLY A 203
CYH A 226
PHE A 227
 None
 1.15A 3ko0D-1iqtA:
undetectable
3ko0E-1iqtA:
undetectable		 3ko0D-1iqtA:
18.02
3ko0E-1iqtA:
18.02