SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ir0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 1ir0 FERREDOXIN
(Bacillus
thermoproteolyti
cus) 		4 / 8 GLY A  60
GLU A  59
ALA A  57
ILE A  66
 None
None
None
SF4  A  82 (-4.8A)
 0.65A 2dtjA-1ir0A:
undetectable
2dtjB-1ir0A:
undetectable		 2dtjA-1ir0A:
18.63
2dtjB-1ir0A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 1ir0 FERREDOXIN
(Bacillus
thermoproteolyti
cus) 		5 / 11 GLY A  60
VAL A   6
GLY A  18
THR A   4
ILE A  66
 None
SF4  A  82 ( 4.6A)
None
None
SF4  A  82 (-4.8A)
 0.93A 4njvB-1ir0A:
undetectable		 4njvB-1ir0A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 1ir0 FERREDOXIN
(Bacillus
thermoproteolyti
cus) 		5 / 11 GLY A  60
VAL A   6
GLY A  18
THR A   4
ILE A  66
 None
SF4  A  82 ( 4.6A)
None
None
SF4  A  82 (-4.8A)
 0.95A 4njvC-1ir0A:
undetectable		 4njvC-1ir0A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 1ir0 FERREDOXIN
(Bacillus
thermoproteolyti
cus) 		5 / 11 ASP A  38
PHE A  73
ILE A  66
TYR A  25
ILE A  24
 None
None
SF4  A  82 (-4.8A)
None
None
 1.27A 5hw8E-1ir0A:
undetectable		 5hw8E-1ir0A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 1ir0 FERREDOXIN
(Bacillus
thermoproteolyti
cus) 		3 / 3 LYS A   2
VAL A  68
ASP A  70
 None
 0.36A 6fgdA-1ir0A:
undetectable		 6fgdA-1ir0A:
13.07