SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1isu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YLD_A_ASCA130_0 (CYTOCHROME C')	1isu	HIGH POTENTIAL IRON SULFUR PROTEIN (Rhodocyclus tenuis)	4 / 5	ALA A 37 GLY A 53 CYH A 22 LYS A 21	None None SF4 A 63 (-2.2A) None	1.44A	2yldA-1isuA: undetectable	2yldA-1isuA: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YLG_A_ASCA130_0 (CYTOCHROME C')	1isu	HIGH POTENTIAL IRON SULFUR PROTEIN (Rhodocyclus tenuis)	4 / 5	ALA A 37 GLY A 53 CYH A 22 LYS A 21	None None SF4 A 63 (-2.2A) None	1.49A	2ylgA-1isuA: undetectable	2ylgA-1isuA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZWI_A_ASCA156_0 (CYTOCHROME C')	1isu	HIGH POTENTIAL IRON SULFUR PROTEIN (Rhodocyclus tenuis)	4 / 5	ALA A 37 GLY A 53 CYH A 22 LYS A 21	None None SF4 A 63 (-2.2A) None	1.43A	3zwiA-1isuA: undetectable	3zwiA-1isuA: 17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JLI_A_ASCA202_0 (CYTOCHROME C')	1isu	HIGH POTENTIAL IRON SULFUR PROTEIN (Rhodocyclus tenuis)	4 / 5	ALA A 37 GLY A 53 CYH A 22 LYS A 21	None None SF4 A 63 (-2.2A) None	1.45A	5jliA-1isuA: undetectable	5jliA-1isuA: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JT4_A_ASCA202_0 (CYTOCHROME C')	1isu	HIGH POTENTIAL IRON SULFUR PROTEIN (Rhodocyclus tenuis)	4 / 5	ALA A 37 GLY A 53 CYH A 22 LYS A 21	None None SF4 A 63 (-2.2A) None	1.45A	5jt4A-1isuA: undetectable	5jt4A-1isuA: 18.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YLD_A_ASCA130_0","CYTOCHROME C'","1isu","HIGH POTENTIAL IRON SULFUR PROTEIN","Rhodocyclus tenuis",4,"ALA A  37;GLY A  53;CYH A  22;LYS A  21","None;None;SF4 A  63 (-2.2A);None","1.44A","2yldA-1isuA:undetectable","2yldA-1isuA:17.97"],["2YLG_A_ASCA130_0","CYTOCHROME C'","1isu","HIGH POTENTIAL IRON SULFUR PROTEIN","Rhodocyclus tenuis",4,"ALA A  37;GLY A  53;CYH A  22;LYS A  21","None;None;SF4 A  63 (-2.2A);None","1.49A","2ylgA-1isuA:undetectable","2ylgA-1isuA:18.11"],["3ZWI_A_ASCA156_0","CYTOCHROME C'","1isu","HIGH POTENTIAL IRON SULFUR PROTEIN","Rhodocyclus tenuis",4,"ALA A  37;GLY A  53;CYH A  22;LYS A  21","None;None;SF4 A  63 (-2.2A);None","1.43A","3zwiA-1isuA:undetectable","3zwiA-1isuA:17.97"],["5JLI_A_ASCA202_0","CYTOCHROME C'","1isu","HIGH POTENTIAL IRON SULFUR PROTEIN","Rhodocyclus tenuis",4,"ALA A  37;GLY A  53;CYH A  22;LYS A  21","None;None;SF4 A  63 (-2.2A);None","1.45A","5jliA-1isuA:undetectable","5jliA-1isuA:18.11"],["5JT4_A_ASCA202_0","CYTOCHROME C'","1isu","HIGH POTENTIAL IRON SULFUR PROTEIN","Rhodocyclus tenuis",4,"ALA A  37;GLY A  53;CYH A  22;LYS A  21","None;None;SF4 A  63 (-2.2A);None","1.45A","5jt4A-1isuA:undetectable","5jt4A-1isuA:18.11"]]