SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1it2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1it2 HEMOGLOBIN
(Eptatretus
burgeri) 		4 / 6 ALA A  48
SER A  51
PHE A  45
ILE A 112
 ALA  A  48 ( 0.0A)
SER  A  51 (-0.0A)
PHE  A  45 ( 1.3A)
ILE  A 112 ( 0.4A)
 1.01A 1yc2A-1it2A:
undetectable		 1yc2A-1it2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 1it2 HEMOGLOBIN
(Eptatretus
burgeri) 		3 / 3 LYS A  78
GLN A  89
ASN A  88
 LYS  A  78 (-0.0A)
GLN  A  89 ( 0.6A)
ASN  A  88 ( 0.6A)
 0.99A 5l2tA-1it2A:
undetectable		 5l2tA-1it2A:
17.97