SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1it5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 1it5 PHOSPHOLIPASE A2
(Streptomyces
violaceoruber) 		3 / 3 ASN A  58
ALA A  62
ASN A  27
 None
 0.83A 1n4fA-1it5A:
0.0		 1n4fA-1it5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1it5 PHOSPHOLIPASE A2
(Streptomyces
violaceoruber) 		4 / 7 ALA A  26
ASP A  39
ARG A  69
GLY A  67
 None
 0.89A 5bs8A-1it5A:
0.0
5bs8C-1it5A:
0.0
5bs8D-1it5A:
undetectable		 5bs8A-1it5A:
12.33
5bs8C-1it5A:
12.33
5bs8D-1it5A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1it5 PHOSPHOLIPASE A2
(Streptomyces
violaceoruber) 		4 / 7 ALA A  26
ASP A  39
ARG A  69
GLY A  67
 None
 0.85A 5btdA-1it5A:
0.0
5btdB-1it5A:
undetectable
5btdC-1it5A:
0.0		 5btdA-1it5A:
12.33
5btdB-1it5A:
17.86
5btdC-1it5A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1it5 PHOSPHOLIPASE A2
(Streptomyces
violaceoruber) 		4 / 7 ALA A  26
ASP A  39
ARG A  69
GLY A  67
 None
 0.84A 5btdA-1it5A:
0.0
5btdC-1it5A:
0.0
5btdD-1it5A:
undetectable		 5btdA-1it5A:
12.33
5btdC-1it5A:
12.33
5btdD-1it5A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1it5 PHOSPHOLIPASE A2
(Streptomyces
violaceoruber) 		4 / 7 ALA A  26
ASP A  39
ARG A  69
GLY A  67
 None
 0.88A 5btgA-1it5A:
undetectable
5btgC-1it5A:
undetectable
5btgD-1it5A:
undetectable		 5btgA-1it5A:
12.33
5btgC-1it5A:
12.33
5btgD-1it5A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 1it5 PHOSPHOLIPASE A2
(Streptomyces
violaceoruber) 		4 / 5 SER A  18
SER A  19
SER A  16
SER A  11
 None
 1.06A 5hswA-1it5A:
0.3		 5hswA-1it5A:
14.78