SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ity'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7N_A_ZMRA601_2 (NEURAMINIDASE)	1ity	TRF1 (Homo sapiens)	3 / 3	ARG A 423 ARG A 380 TRP A 383	None	1.39A	4b7nA-1ityA: undetectable	4b7nA-1ityA: 8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_C_ZMRC1470_2 (NEURAMINIDASE)	1ity	TRF1 (Homo sapiens)	3 / 3	ARG A 423 ARG A 380 TRP A 383	None	1.36A	4cpzC-1ityA: undetectable	4cpzC-1ityA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_E_ZMRE1471_2 (NEURAMINIDASE)	1ity	TRF1 (Homo sapiens)	3 / 3	ARG A 423 ARG A 380 TRP A 383	None	1.38A	4cpzE-1ityA: undetectable	4cpzE-1ityA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_F_ZMRF1470_2 (NEURAMINIDASE)	1ity	TRF1 (Homo sapiens)	3 / 3	ARG A 423 ARG A 380 TRP A 383	None	1.32A	4cpzF-1ityA: undetectable	4cpzF-1ityA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_G_ZMRG1471_2 (NEURAMINIDASE)	1ity	TRF1 (Homo sapiens)	3 / 3	ARG A 423 ARG A 380 TRP A 383	None	1.41A	4cpzG-1ityA: undetectable	4cpzG-1ityA: 10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CPZ_H_ZMRH1470_2 (NEURAMINIDASE)	1ity	TRF1 (Homo sapiens)	3 / 3	ARG A 423 ARG A 380 TRP A 383	None	1.31A	4cpzH-1ityA: undetectable	4cpzH-1ityA: 10.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4B7N_A_ZMRA601_2","NEURAMINIDASE","1ity","TRF1","Homo sapiens",3,"ARG A 423;ARG A 380;TRP A 383","None","1.39A","4b7nA-1ityA:undetectable","4b7nA-1ityA:8.70"],["4CPZ_C_ZMRC1470_2","NEURAMINIDASE","1ity","TRF1","Homo sapiens",3,"ARG A 423;ARG A 380;TRP A 383","None","1.36A","4cpzC-1ityA:undetectable","4cpzC-1ityA:10.31"],["4CPZ_E_ZMRE1471_2","NEURAMINIDASE","1ity","TRF1","Homo sapiens",3,"ARG A 423;ARG A 380;TRP A 383","None","1.38A","4cpzE-1ityA:undetectable","4cpzE-1ityA:10.31"],["4CPZ_F_ZMRF1470_2","NEURAMINIDASE","1ity","TRF1","Homo sapiens",3,"ARG A 423;ARG A 380;TRP A 383","None","1.32A","4cpzF-1ityA:undetectable","4cpzF-1ityA:10.31"],["4CPZ_G_ZMRG1471_2","NEURAMINIDASE","1ity","TRF1","Homo sapiens",3,"ARG A 423;ARG A 380;TRP A 383","None","1.41A","4cpzG-1ityA:undetectable","4cpzG-1ityA:10.31"],["4CPZ_H_ZMRH1470_2","NEURAMINIDASE","1ity","TRF1","Homo sapiens",3,"ARG A 423;ARG A 380;TRP A 383","None","1.31A","4cpzH-1ityA:undetectable","4cpzH-1ityA:10.31"]]