SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iu9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 187
GLU A 183
LEU A 182
MET A 145
 None
 0.93A 1hk2A-1iu9A:
3.0		 1hk2A-1iu9A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A 172
VAL A 155
THR A 178
 None
 0.74A 2nmzA-1iu9A:
0.0		 2nmzA-1iu9A:
25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A 172
VAL A 155
THR A 178
 None
 0.82A 2nnkA-1iu9A:
undetectable		 2nnkA-1iu9A:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		4 / 7 GLY A 120
ILE A 211
THR A 107
LEU A 121
 None
 1.01A 2xrhA-1iu9A:
undetectable		 2xrhA-1iu9A:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A 172
VAL A 155
THR A 178
 None
 0.78A 3pwrA-1iu9A:
undetectable		 3pwrA-1iu9A:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A 172
VAL A 155
THR A 178
 None
 0.87A 3tl9A-1iu9A:
undetectable		 3tl9A-1iu9A:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 193
LEU A 121
VAL A 132
THR A 107
ILE A 211
 None
 1.35A 4okbA-1iu9A:
undetectable		 4okbA-1iu9A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 193
ILE A 211
LEU A 210
GLY A 120
GLY A 131
 None
 1.07A 5d4uA-1iu9A:
undetectable		 5d4uA-1iu9A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 1iu9 ASPARTATE RACEMASE
(Pyrococcus
horikoshii) 		5 / 12 GLY A 193
ILE A 211
LEU A 210
GLY A 120
GLY A 131
 None
 1.07A 5d4uB-1iu9A:
undetectable		 5d4uB-1iu9A:
19.01