SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iub'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3004_0
(BETA-CARBONIC
ANHYDRASE)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 6 GLN A  28
CYH A  80
VAL A  78
GLY A  55
 None
HG  A 421 (-2.4A)
None
None
 1.13A 1ekjC-1iubA:
undetectable
1ekjD-1iubA:
undetectable		 1ekjC-1iubA:
24.10
1ekjD-1iubA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 6 LEU A 115
LEU A 102
GLY A 103
ILE A  86
 None
 0.83A 1mt1G-1iubA:
undetectable
1mt1J-1iubA:
0.0		 1mt1G-1iubA:
11.56
1mt1J-1iubA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 7 ILE A  86
LEU A 115
LEU A 102
GLY A 103
 None
 0.83A 1mt1H-1iubA:
0.0
1mt1K-1iubA:
undetectable		 1mt1H-1iubA:
15.02
1mt1K-1iubA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 LEU A 115
LEU A 102
GLY A 103
ILE A  86
 None
 0.84A 1n13A-1iubA:
undetectable
1n13F-1iubA:
undetectable		 1n13A-1iubA:
11.56
1n13F-1iubA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		5 / 10 LYS A   1
VAL A 285
TYR A   6
GLY A 284
LEU A   5
 None
 1.33A 1s1uA-1iubA:
undetectable		 1s1uA-1iubA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_B_EDTB1511_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 TYR A 241
TRP A 245
TYR A 181
THR A 171
 None
 1.47A 1zlqB-1iubA:
undetectable		 1zlqB-1iubA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 ILE A  86
LEU A 115
LEU A 102
GLY A 103
 None
 0.83A 2qqcH-1iubA:
undetectable
2qqcK-1iubA:
undetectable		 2qqcH-1iubA:
15.02
2qqcK-1iubA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 ILE A  86
LEU A 115
LEU A 102
GLY A 103
 None
 0.82A 2qqdB-1iubA:
0.0
2qqdC-1iubA:
0.0		 2qqdB-1iubA:
15.02
2qqdC-1iubA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		5 / 11 ILE A 276
ASP A 275
ILE A 274
GLY A 272
GLY A 220
 None
None
None
CL  A 412 ( 4.8A)
None
 0.95A 4ac9B-1iubA:
undetectable
4ac9C-1iubA:
undetectable		 4ac9B-1iubA:
20.33
4ac9C-1iubA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 ILE A 276
ASP A 275
ILE A 274
GLY A 220
 None
 0.67A 4ac9C-1iubA:
undetectable		 4ac9C-1iubA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 ILE A 276
ASP A 275
ILE A 274
GLY A 220
 None
 0.71A 4acaC-1iubA:
undetectable		 4acaC-1iubA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 ILE A 276
ASP A 275
ILE A 274
GLY A 220
 None
 0.76A 4acbC-1iubA:
undetectable		 4acbC-1iubA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 7 ALA A 172
PRO A 175
TYR A 133
LEU A 118
 None
 0.98A 4iomA-1iubA:
undetectable		 4iomA-1iubA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		5 / 12 ALA A  12
THR A 306
PHE A   4
ILE A  10
SER A   8
 None
 1.43A 5hgcA-1iubA:
undetectable		 5hgcA-1iubA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 TYR A 241
TRP A 245
TYR A 181
THR A 171
 None
 1.46A 5l8dA-1iubA:
0.0		 5l8dA-1iubA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		4 / 8 TYR A 241
TRP A 245
TYR A 181
THR A 171
 None
 1.46A 5mwuA-1iubA:
0.0		 5mwuA-1iubA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 1iub FUCOSE-SPECIFIC
LECTIN
(Aleuria
aurantia) 		5 / 12 ILE A 266
GLY A 169
ALA A 215
ALA A 116
ALA A 117
 None
 1.04A 5zw4A-1iubA:
undetectable		 5zw4A-1iubA:
21.81