SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1iuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU A  33
GLY A  29
LEU A  24
TYR A  20
 None
 0.81A 1gtiA-1iufA:
undetectable		 1gtiA-1iufA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU A  33
GLY A  29
LEU A  24
TYR A  20
 None
 0.82A 1gtiB-1iufA:
undetectable		 1gtiB-1iufA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU A  33
GLY A  29
LEU A  24
TYR A  20
 None
 0.82A 1gtiD-1iufA:
undetectable		 1gtiD-1iufA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 LEU A  33
GLY A  29
LEU A  24
TYR A  20
 None
 0.82A 1gtiE-1iufA:
undetectable		 1gtiE-1iufA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP A 120
GLN A 121
PRO A 116
GLU A 117
 None
 0.82A 3l2vA-1iufA:
undetectable		 3l2vA-1iufA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLD_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 6 TRP A 130
PHE A 126
GLU A 132
TRP A  89
 None
 1.41A 3nldA-1iufA:
0.0
3nldB-1iufA:
0.8		 3nldA-1iufA:
13.92
3nldB-1iufA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 8 ASP A 120
GLN A 121
PRO A 116
GLU A 117
 None
 0.86A 3oyaA-1iufA:
undetectable		 3oyaA-1iufA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU A  54
LEU A  33
ARG A   7
 None
 0.50A 5hnzB-1iufA:
undetectable		 5hnzB-1iufA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1iuf CENTROMERE ABP1
PROTEIN
(Schizosaccharomy
ces
pombe) 		4 / 6 TRP A 130
PHE A 126
GLU A 132
TRP A  89
 None
 1.42A 6cifA-1iufA:
0.0
6cifB-1iufA:
0.0		 6cifA-1iufA:
21.01
6cifB-1iufA:
21.01